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Year Number of Results
1975 1
1977 1
1980 2
1992 1
1995 1
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1999 2
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2003 1
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2019 1
2024 0

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Page 1
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Shehabi Y, Howe BD, Bellomo R, Arabi YM, Bailey M, Bass FE, Bin Kadiman S, McArthur CJ, Murray L, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA; ANZICS Clinical Trials Group and the SPICE III Investigators. Shehabi Y, et al. N Engl J Med. 2019 Jun 27;380(26):2506-2517. doi: 10.1056/NEJMoa1904710. Epub 2019 May 19. N Engl J Med. 2019. PMID: 31112380 Clinical Trial.
Introduction: glutamate transport, metabolism, and physiological responses.
Hediger MA, Welbourne TC. Hediger MA, et al. Am J Physiol. 1999 Oct;277(4):F477-80. doi: 10.1152/ajprenal.1999.277.4.F477. Am J Physiol. 1999. PMID: 10516268 Review.
Nissim provides an overview of the significant role of pH in regulating Gln/Glu metabolism in the kidney, liver, and brain. J. D. McGivan and B. Nicholson describe some characteristics of glutamate transport regulation with regard to a specific experimental model of …
Nissim provides an overview of the significant role of pH in regulating Gln/Glu metabolism in the kidney, liver, and brain. J. D …
Glutamate transport asymmetry in renal glutamine metabolism.
Carter P, Welbourne TC. Carter P, et al. Am J Physiol. 1998 May;274(5):E877-84. doi: 10.1152/ajpendo.1998.274.5.E877. Am J Physiol. 1998. PMID: 9612246
D-Glutamate (Glu) was previously shown to block L-Glu uptake and accelerate glutaminase flux in cultured kidney cells [Welbourne, T. C., and D. Chevalier. Am. J. Physiol. 272 (Endocrinol. Metab. 35): E367-E370, 1997]. ...
D-Glutamate (Glu) was previously shown to block L-Glu uptake and accelerate glutaminase flux in cultured kidney cells [Welbourne …
Regulatory responses to an oral D-glutamate load: formation of D-pyrrolidone carboxylic acid in humans.
Raj D, Langford M, Krueger S, Shelton M, Welbourne T. Raj D, et al. Am J Physiol Endocrinol Metab. 2001 Feb;280(2):E214-20. doi: 10.1152/ajpendo.2001.280.2.E214. Am J Physiol Endocrinol Metab. 2001. PMID: 11158923 Free article.
Excretion of D-glutamate progressively increased despite a constant filtered D-glutamate load rising from only 5 to 95% of the filtered amount. ...The amount of D-pyrrolidone carboxylic acid excreted over the 3-h time course was 10 times the amount excreted a …
Excretion of D-glutamate progressively increased despite a constant filtered D-glutamate load rising from only 5 to 95% of the …
Renal glutamine utilization: glycylglycine stimulation of gamma-glutamyltransferase.
Welbourne TC, Dass PD, Smith RL. Welbourne TC, et al. Can J Biochem. 1980 Aug;58(8):614-9. doi: 10.1139/o80-084. Can J Biochem. 1980. PMID: 6109560
In the crude systems, containing cyclotransferase, the gamma-glutamyl moiety appears mainly as 5-oxoproline; however, in the enzyme preparation, purified 112-fold, gamma-glutamyl peptides (transpeptidation) and a small amount of glutamate (hydrolysis) appear. D-Glutamine w …
In the crude systems, containing cyclotransferase, the gamma-glutamyl moiety appears mainly as 5-oxoproline; however, in the enzyme preparat …
Glutamate transport asymmetry and metabolism in the functioning kidney.
Schuldt S, Carter P, Welbourne T. Schuldt S, et al. Am J Physiol. 1999 Sep;277(3):E439-46. doi: 10.1152/ajpendo.1999.277.3.E439. Am J Physiol. 1999. PMID: 10484355
Equimolar D-aspartate concentration blocked most of the antiluminal D-glutamate uptake and a significant portion of the luminal L-glutamate uptake, consistent with system X-AG activity at both sites. D-Glutamate uptake was associated with 5-oxo-D-proli …
Equimolar D-aspartate concentration blocked most of the antiluminal D-glutamate uptake and a significant portion of the lumina …
Extracellular glutamate flux regulates intracellular glutaminase activity in LLC-PK1-F+ cells.
Welbourne TC, Mu X. Welbourne TC, et al. Am J Physiol. 1995 Jun;268(6 Pt 1):C1418-24. doi: 10.1152/ajpcell.1995.268.6.C1418. Am J Physiol. 1995. PMID: 7611361
To test this, cellular glutamate uptake and extracellular production were inhibited for 18 h by the addition of D-aspartate (10 mM) or acivicin (0.7 mM) to both apical and basal media. ...Intracellular relative glutaminase activity, monitored as the breakdown of 14C-radiol …
To test this, cellular glutamate uptake and extracellular production were inhibited for 18 h by the addition of D-aspartate (10 mM) o …
Regulation of mitochondrial glutamine/glutamate metabolism by glutamate transport: studies with (15)N.
Welbourne T, Nissim I. Welbourne T, et al. Am J Physiol Cell Physiol. 2001 May;280(5):C1151-9. doi: 10.1152/ajpcell.2001.280.5.C1151. Am J Physiol Cell Physiol. 2001. PMID: 11287328 Free article.
We focused on the role of plasma membrane glutamate uptake in modulating the intracellular glutaminase (GA) and glutamate dehydrogenase (GDH) flux and in determining the fate of the intracellular glutamate in the proximal tubule-like LLC-PK(1)-F(+) cell line. We used high-affinit …
We focused on the role of plasma membrane glutamate uptake in modulating the intracellular glutaminase (GA) and glutamate dehydrogenase (GDH …
Using parallel distributed processing models to simulate phonological dyslexia: the key role of plasticity-related recovery.
Welbourne SR, Lambon Ralph MA. Welbourne SR, et al. J Cogn Neurosci. 2007 Jul;19(7):1125-39. doi: 10.1162/jocn.2007.19.7.1125. J Cogn Neurosci. 2007. PMID: 17583989
PMSP96 [Plaut, D. C., McClelland, J. L., Seidenberg, M. S., & Patterson, K. Understanding normal and impaired word reading: Computational principles in quasi-regular domains. ...
PMSP96 [Plaut, D. C., McClelland, J. L., Seidenberg, M. S., & Patterson, K. Understanding normal and impaired word reading …
Influence of aldosterone on renal ammonia production.
Welbourne TC, Francoeur D. Welbourne TC, et al. Am J Physiol. 1977 Jul;233(1):E56-60. doi: 10.1152/ajpendo.1977.233.1.E56. Am J Physiol. 1977. PMID: 18022
Administering D-aldosterone, 7 microgram 100 g-1, to rats results in a marked rise in ammonium excretion and metabolic alkalosis. ...
Administering D-aldosterone, 7 microgram 100 g-1, to rats results in a marked rise in ammonium excretion and metabolic alkalosis. ...
18 results