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1982 2
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Page 1
Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis.
Simpson EL, Bieber T, Guttman-Yassky E, Beck LA, Blauvelt A, Cork MJ, Silverberg JI, Deleuran M, Kataoka Y, Lacour JP, Kingo K, Worm M, Poulin Y, Wollenberg A, Soo Y, Graham NM, Pirozzi G, Akinlade B, Staudinger H, Mastey V, Eckert L, Gadkari A, Stahl N, Yancopoulos GD, Ardeleanu M; SOLO 1 and SOLO 2 Investigators. Simpson EL, et al. N Engl J Med. 2016 Dec 15;375(24):2335-2348. doi: 10.1056/NEJMoa1610020. Epub 2016 Sep 30. N Engl J Med. 2016. PMID: 27690741 Free article. Clinical Trial.
Two Phase 3 Trials of Lebrikizumab for Moderate-to-Severe Atopic Dermatitis.
Silverberg JI, Guttman-Yassky E, Thaçi D, Irvine AD, Stein Gold L, Blauvelt A, Simpson EL, Chu CY, Liu Z, Gontijo Lima R, Pillai SG, Seneschal J; ADvocate1 and ADvocate2 Investigators. Silverberg JI, et al. N Engl J Med. 2023 Mar 23;388(12):1080-1091. doi: 10.1056/NEJMoa2206714. Epub 2023 Mar 15. N Engl J Med. 2023. PMID: 36920778 Clinical Trial.
Cell-free V(D)J recombination.
Ramsden DA, Paull TT, Gellert M. Ramsden DA, et al. Nature. 1997 Jul 31;388(6641):488-91. doi: 10.1038/41351. Nature. 1997. PMID: 9242409
V(D)J recombination generates diversity in the immune system through the lymphoid-specific assembly of multiple gene segments into functional immunoglobulin and T-cell receptor genes. The first step in V(D)J recombination is cleavage of DNA at recombin …
V(D)J recombination generates diversity in the immune system through the lymphoid-specific assembly of multiple gene segments …
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
Lagomarsino VN, Pearse RV 2nd, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, Fancher SB, He A, Merchant JP, Duong DM, Martinez H, Zhou M, Bah F, Vicent MA, Stricker JMS, Xu J, Dammer EB, Levey AI, Chibnik LB, Menon V, Seyfried NT, De Jager PL, Noggle S, Selkoe DJ, Bennett DA, Young-Pearse TL. Lagomarsino VN, et al. Neuron. 2021 Nov 3;109(21):3402-3420.e9. doi: 10.1016/j.neuron.2021.08.003. Epub 2021 Sep 1. Neuron. 2021. PMID: 34473944 Free PMC article.
V(D)J recombination: links to transposition and double-strand break repair.
Gellert M, Hesse JE, Hiom K, Melek M, Modesti M, Paull TT, Ramsden DA, van Gent DC. Gellert M, et al. Cold Spring Harb Symp Quant Biol. 1999;64:161-7. doi: 10.1101/sqb.1999.64.161. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232281 Review. No abstract available.
Human brain atlasing: past, present and future.
Nowinski WL. Nowinski WL. Neuroradiol J. 2017 Dec;30(6):504-519. doi: 10.1177/1971400917739274. Epub 2017 Nov 3. Neuroradiol J. 2017. PMID: 29096577 Free PMC article. Review.
My contribution to these global efforts has been to create adult human brain atlases in health and disease, and to develop atlas-based applications. For over two decades with my R&D lab I developed 35 brain atlases, licensed to 67 companies and made available in about …
My contribution to these global efforts has been to create adult human brain atlases in health and disease, and to develop atlas-based appli …
Stimulation of V(D)J cleavage by high mobility group proteins.
van Gent DC, Hiom K, Paull TT, Gellert M. van Gent DC, et al. EMBO J. 1997 May 15;16(10):2665-70. doi: 10.1093/emboj/16.10.2665. EMBO J. 1997. PMID: 9184213 Free PMC article.
V(D)J recombination requires a pair of signal sequences with spacer lengths of 12 and 23 bp between the conserved heptamer and nonamer elements. ...
V(D)J recombination requires a pair of signal sequences with spacer lengths of 12 and 23 bp between the conserved heptamer and …
MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.
Hung PJ, Johnson B, Chen BR, Byrum AK, Bredemeyer AL, Yewdell WT, Johnson TE, Lee BJ, Deivasigamani S, Hindi I, Amatya P, Gross ML, Paull TT, Pisapia DJ, Chaudhuri J, Petrini JJH, Mosammaparast N, Amarasinghe GK, Zha S, Tyler JK, Sleckman BP. Hung PJ, et al. Mol Cell. 2018 Jul 19;71(2):332-342.e8. doi: 10.1016/j.molcel.2018.06.018. Epub 2018 Jul 12. Mol Cell. 2018. PMID: 30017584 Free PMC article.
Can simple tank changes benefit the welfare of laboratory zebrafish Danio rerio?
Lee CJ, Tyler CR, Paull GC. Lee CJ, et al. J Fish Biol. 2018 Mar;92(3):653-659. doi: 10.1111/jfb.13535. Epub 2018 Jan 24. J Fish Biol. 2018. PMID: 29363145
This study examined the effects of simple changes in the tank environment on the wellbeing of laboratory-maintained zebrafish Danio rerio. Groups of D. rerio were either housed in stable environments (where they were maintained in the same tanks throughout the study) or in …
This study examined the effects of simple changes in the tank environment on the wellbeing of laboratory-maintained zebrafish Danio rerio. G …
40 results