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1990 1
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56 results

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Page 1
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.
Dhavale DD, Barclay AM, Borcik CG, Basore K, Berthold DA, Gordon IR, Liu J, Milchberg MH, O'Shea JY, Rau MJ, Smith Z, Sen S, Summers B, Smith J, Warmuth OA, Perrin RJ, Perlmutter JS, Chen Q, Fitzpatrick JAJ, Schwieters CD, Tajkhorshid E, Rienstra CM, Kotzbauer PT. Dhavale DD, et al. Nat Commun. 2024 Mar 29;15(1):2750. doi: 10.1038/s41467-024-46832-5. Nat Commun. 2024. PMID: 38553463 Free PMC article.
D-Glucose-Derived 1,2,4-Trioxepanes: Synthesis, Conformational Study, and Antimalarial Activity.
Sonawane DP, Corbett Y, Dhavale DD, Taramelli D, Trombini C, Quintavalla A, Lombardo M. Sonawane DP, et al. Org Lett. 2015 Aug 21;17(16):4074-7. doi: 10.1021/acs.orglett.5b01996. Epub 2015 Aug 3. Org Lett. 2015. PMID: 26237035
New enantiomerically pure 1,2,4-trioxepanes 10a,b/11a,b were synthesized from D-glucose. Their conformational behavior was studied by low-temperature NMR and substantiated by DFT calculations. ...
New enantiomerically pure 1,2,4-trioxepanes 10a,b/11a,b were synthesized from D-glucose. Their conformational behavior was studied by …
Halogenated D-xylono-delta-lactams: synthesis and enzyme inhibition study.
Bhuma N, Vangala M, Nair RJ, Sabharwal SG, Dhavale DD. Bhuma N, et al. Carbohydr Res. 2015 Jan 30;402:215-24. doi: 10.1016/j.carres.2014.10.023. Epub 2014 Oct 31. Carbohydr Res. 2015. PMID: 25498022
A concise synthesis of four C-3 fluoro/chloro-D-xylono-delta-lactams 3/4 has been reported. The methodology involves Corey-Link approach with suitably protected 3-oxo-D-gluco-furanose to introduce F/Cl as well as ester/amide functionalities at C-3 of glucose. ...
A concise synthesis of four C-3 fluoro/chloro-D-xylono-delta-lactams 3/4 has been reported. The methodology involves Corey-Link appro …
COVID-19 and Aortic Thrombosis: A Case Report.
Balla M, Staats-Ciotola H, Dhavale M, Sangani V, Pokal M, Merugu GP, Konala VM, Adapa S, Naramala S, Rallabhandi SSH. Balla M, et al. J Community Hosp Intern Med Perspect. 2022 May 2;12(3):94-99. doi: 10.55729/2000-9666.1060. eCollection 2022. J Community Hosp Intern Med Perspect. 2022. PMID: 35711404 Free PMC article.
An efficient synthesis of D-erythro- and D-threo-sphingosine from D-glucose: olefin cross-metathesis approach.
Chaudhari VD, Kumar KS, Dhavale DD. Chaudhari VD, et al. Org Lett. 2005 Dec 22;7(26):5805-7. doi: 10.1021/ol052320z. Org Lett. 2005. PMID: 16354071
[reaction: see text] The D-erythro- and D-threo-sphingosine were synthesized via E-selective olefin cross-metathesis using a D-glucose-derived building block and long-chain terminal alkene....
[reaction: see text] The D-erythro- and D-threo-sphingosine were synthesized via E-selective olefin cross-metathesis using a …
1,3-Dipolar cycloaddition reaction of D-glucose-derived nitrone with allyl alcohol: synthesis of 2-hydroxy-1-deoxycastanospermine analogues.
Karanjule NS, Markad SD, Sharma T, Sabharwal SG, Puranik VG, Dhavale DD. Karanjule NS, et al. J Org Chem. 2005 Feb 18;70(4):1356-63. doi: 10.1021/jo048176x. J Org Chem. 2005. PMID: 15704970
[reaction: see text] The synthesis and evaluation of glycosidase inhibitory activity of polyhydroxylated indolizidine alkaloids namely 2-hydroxy-1-deoxycastanospermine 3a,b and 2-hydroxy-1-deoxy-8a-epi-castanospermine 3c,d is reported. The key step involves the intermolecu …
[reaction: see text] The synthesis and evaluation of glycosidase inhibitory activity of polyhydroxylated indolizidine alkaloids namely 2-hyd …
Diosgenin Functionalized Iron Oxide Nanoparticles as Novel Nanomaterial Against Breast Cancer.
Ghosh S, More P, Derle A, Kitture R, Kale T, Gorain M, Avasthi A, Markad P, Kundu GC, Kale S, Dhavale DD, Bellare J, Chopade BA. Ghosh S, et al. J Nanosci Nanotechnol. 2015 Dec;15(12):9464-72. doi: 10.1166/jnn.2015.11704. J Nanosci Nanotechnol. 2015. PMID: 26682367
Size of IONPs, IONPs-CA and IONPs-D gradually increased ranging from 12 to 21 nm as confirmed by FESEM and HRTEM. ...IONPs-D mediated selective PARP cleavage strongly rationalized it as superior apoptotic inducers. ...
Size of IONPs, IONPs-CA and IONPs-D gradually increased ranging from 12 to 21 nm as confirmed by FESEM and HRTEM. ...IONPs-D m …
Catechuic acid and ethyl 2,4,5-trihydroxybenzoate from D-glucose.
Bhujbal NN, Bande OP, Dhavale DD. Bhujbal NN, et al. Carbohydr Res. 2009 Apr 21;344(6):734-8. doi: 10.1016/j.carres.2009.02.002. Epub 2009 Feb 8. Carbohydr Res. 2009. PMID: 19268918
Synthesis of catechuic acid (1) and ethyl 2,4,5-trihydroxybenzoate (2) from D-glucose-derived beta-ketoester is described. The polyhydroxylated beta-ketoester obtained from the hydrolysis of sugar beta-ketoester 3 was subjected to an aldol-type condensation to get 4 that o …
Synthesis of catechuic acid (1) and ethyl 2,4,5-trihydroxybenzoate (2) from D-glucose-derived beta-ketoester is described. The polyhy …
Synthesis and evaluation of glycosidase inhibitory activity of N-butyl 1-deoxy-D-gluco-homonojirimycin and N-butyl 1-deoxy-L-ido-homonojirimycin.
Markad SD, Karanjule NS, Sharma T, Sabharwal SG, Dhavale DD. Markad SD, et al. Bioorg Med Chem. 2006 Aug 15;14(16):5535-9. doi: 10.1016/j.bmc.2006.04.027. Epub 2006 May 8. Bioorg Med Chem. 2006. PMID: 16682208
Conjugate addition of n-butyl amine to d-glucose derived alpha,beta-unsaturated ester 4 afforded beta-amino esters 5a,b that on reduction of ester group, 1,2-acetonide deprotection, and reductive amination led to the formation of corresponding N-butyl 1-deoxy-D-gluc …
Conjugate addition of n-butyl amine to d-glucose derived alpha,beta-unsaturated ester 4 afforded beta-amino esters 5a,b that on reduc …
56 results