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Fetal abdominal tumors and cysts.
Cass DL. Cass DL. Transl Pediatr. 2021 May;10(5):1530-1541. doi: 10.21037/tp-20-440. Transl Pediatr. 2021. PMID: 34189111 Free PMC article. Review.
Perinatal management of the fetus with a neoplasm requires consideration of the optimal timing and mode of delivery, and pediatric oncology and surgical specialty care. The majority of tumors diagnosed antenatally have good prognosis with current multimodality treat …
Perinatal management of the fetus with a neoplasm requires consideration of the optimal timing and mode of delivery, and pediatric oncolo
Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion.
Battistello E, Hixon KA, Comstock DE, Collings CK, Chen X, Rodriguez Hernaez J, Lee S, Cervantes KS, Hinkley MM, Ntatsoulis K, Cesarano A, Hockemeyer K, Haining WN, Witkowski MT, Qi J, Tsirigos A, Perna F, Aifantis I, Kadoch C. Battistello E, et al. Mol Cell. 2023 Apr 20;83(8):1216-1236.e12. doi: 10.1016/j.molcel.2023.02.026. Epub 2023 Mar 20. Mol Cell. 2023. PMID: 36944333 Free PMC article.
These findings reveal the central role of mSWI/SNF complexes in the coordination of T cell activation and exhaustion and nominate small-molecule-based strategies for the improvement of current immunotherapy protocols....
These findings reveal the central role of mSWI/SNF complexes in the coordination of T cell activation and exhaustion and nominate small-mole …
Designing the next-generation clinical care pathway for Alzheimer's disease.
Hampel H, Au R, Mattke S, van der Flier WM, Aisen P, Apostolova L, Chen C, Cho M, De Santi S, Gao P, Iwata A, Kurzman R, Saykin AJ, Teipel S, Vellas B, Vergallo A, Wang H, Cummings J. Hampel H, et al. Nat Aging. 2022 Aug;2(8):692-703. doi: 10.1038/s43587-022-00269-x. Epub 2022 Aug 19. Nat Aging. 2022. PMID: 37118137 Free PMC article. Review.
In this Perspective, we describe the blueprint for transitioning from the current, clinical symptom-focused and inherently late-stage diagnosis and management of AD to the next-generation pathway that incorporates biomarker-guided and digitally facilitated decision-making …
In this Perspective, we describe the blueprint for transitioning from the current, clinical symptom-focused and inherently late-stage …
Open partial nephrectomy: current review.
O'Connor E, Timm B, Lawrentschuk N, Ischia J. O'Connor E, et al. Transl Androl Urol. 2020 Dec;9(6):3149-3159. doi: 10.21037/tau-20-474. Transl Androl Urol. 2020. PMID: 33457287 Free PMC article. Review.
OPN has several advantages, particularly in complex patients such as those with a solitary kidney, multi-focal tumors, and significant surgical history, as well as providing improved application of renoprotective measures. As such, it is a technique that remains relevant in cu
OPN has several advantages, particularly in complex patients such as those with a solitary kidney, multi-focal tumors, and significant surgi …
Understanding breast cancer disparities-a multi-scale challenge.
Hill HE, Schiemann WP, Varadan V. Hill HE, et al. Ann Transl Med. 2020 Jul;8(14):906. doi: 10.21037/atm.2020.04.37. Ann Transl Med. 2020. PMID: 32793750 Free PMC article. Review.
This review explores the complex multi-factorial nature of tumor-intrinsic and -extrinsic factors that impact the biology and clinical outcomes of breast cancer patients. In addition to summarizing the current state of breast cancer disparities research, we also motivate t …
This review explores the complex multi-factorial nature of tumor-intrinsic and -extrinsic factors that impact the biology and clinical outco …
Robotic-assisted laparoscopy in pediatric surgical oncology: a narrative review.
Vinit N, Sarnacki S, Blanc T. Vinit N, et al. Transl Pediatr. 2023 Dec 26;12(12):2256-2266. doi: 10.21037/tp-23-251. Epub 2023 Dec 18. Transl Pediatr. 2023. PMID: 38197107 Free PMC article. Review.
The aim of this review was to analyze the current state of robotic-assisted laparoscopy in pediatric tumor resection, assess the necessary framework of minimally invasive surgical oncology and describe future developments of the robotic technology. ...KEY CONTENT AN …
The aim of this review was to analyze the current state of robotic-assisted laparoscopy in pediatric tumor resection, assess the nece …
Venous thromboembolism in musculoskeletal oncology surgery.
Donahue A, Sobol KR, Abraham JA. Donahue A, et al. Ann Jt. 2022 Oct 15;7:39. doi: 10.21037/aoj-20-107. eCollection 2022. Ann Jt. 2022. PMID: 38529127 Free PMC article. Review.
Venous thromboembolism (VTE), including both deep venous thrombosis (DVT) and pulmonary embolism (PE), is a major complication of musculoskeletal surgery in general, and the risk is heightened in musculoskeletal oncology surgery. Despite the well-known association between …
Venous thromboembolism (VTE), including both deep venous thrombosis (DVT) and pulmonary embolism (PE), is a major complication of musculoske …
Mechanisms of resistance to osimertinib.
Lazzari C, Gregorc V, Karachaliou N, Rosell R, Santarpia M. Lazzari C, et al. J Thorac Dis. 2020 May;12(5):2851-2858. doi: 10.21037/jtd.2019.08.30. J Thorac Dis. 2020. PMID: 32642198 Free PMC article. Review.
Moreover, osimertinib has shown significant central nervous system (CNS) activity and a favorable safety profile. The current review focuses on the clinical development of osimertinib, the mechanisms of acquired resistance identified in patients receiving osimertinib and t …
Moreover, osimertinib has shown significant central nervous system (CNS) activity and a favorable safety profile. The current review …
173 results