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Year Number of Results
1980 1
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1989 1
1990 1
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1999 1
2000 2
2002 2
2003 1
2004 3
2005 5
2006 2
2008 3
2009 4
2010 1
2011 3
2013 3
2014 2
2015 2
2016 4
2017 5
2018 2
2019 3
2020 4
2021 1
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2023 4
2024 0

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60 results

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Page 1
Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Liu Z, Lee PG, Krez N, Lam KH, Liu H, Przykopanski A, Chen P, Yao G, Zhang S, Tremblay JM, Perry K, Shoemaker CB, Rummel A, Dong M, Jin R. Liu Z, et al. Nat Commun. 2023 Apr 24;14(1):2338. doi: 10.1038/s41467-023-37860-8. Nat Commun. 2023. PMID: 37095076 Free PMC article.
Botulinum neurotoxin E (BoNT/E) is one of the major causes of human botulism and paradoxically also a promising therapeutic agent. Here we determined the co-crystal structures of the receptor-binding domain of BoNT/E (H(C)E) in complex with its neuronal receptor synaptic v …
Botulinum neurotoxin E (BoNT/E) is one of the major causes of human botulism and paradoxically also a promising therapeutic agent. Here we d …
Structural Diversity in 2,2'-[Naphthalene-1,8:4,5-bis(dicarboximide)-N,N'-diyl]-bis(ethylammonium) Iodoplumbates.
Tremblay MH, Zeidell AM, Rigin S, Tyznik C, Bacsa J, Zhang Y, Al Kurdi K, Jurchescu OD, Timofeeva TV, Barlow S, Marder SR. Tremblay MH, et al. Inorg Chem. 2020 Jun 15;59(12):8070-8080. doi: 10.1021/acs.inorgchem.0c00165. Epub 2020 Jun 1. Inorg Chem. 2020. PMID: 32478526
Crystallization from solutions containing 2,2'-[naphthalene-1,8:4,5-bis(dicarboximide)-N,N'-diyl]-bis(ethylammonium) diiodide ((NDIC2)I(2)) and PbI(2) has been investigated. Eight different materials are obtained, either by variation of crystallization conditions or …
Crystallization from solutions containing 2,2'-[naphthalene-1,8:4,5-bis(dicarboximide)-N,N'-diyl]-bis(ethylammonium) diiodide ((NDIC2 …
Crystal-clear urine and infection.
Tremblay S, Labbé J. Tremblay S, et al. Lancet. 1994 Feb 19;343(8895):479-80. doi: 10.1016/s0140-6736(94)92723-5. Lancet. 1994. PMID: 7905972 No abstract available.
Crystal structure of the receptor-binding protein head domain from Lactococcus lactis phage bIL170.
Ricagno S, Campanacci V, Blangy S, Spinelli S, Tremblay D, Moineau S, Tegoni M, Cambillau C. Ricagno S, et al. J Virol. 2006 Sep;80(18):9331-5. doi: 10.1128/JVI.01160-06. J Virol. 2006. PMID: 16940545 Free PMC article.
In the first step of infection, phages recognize the host saccharidic receptor using their receptor binding protein (RBP). Here, we report the 2.30-A-resolution crystal structure of the RBP head domain from phage bIL170. The structure of the head monomer is remarkably clos …
In the first step of infection, phages recognize the host saccharidic receptor using their receptor binding protein (RBP). Here, we report t …
Versatile iodine-doped BiOCl with abundant oxygen vacancies and (110) crystal planes for enhanced pollutant photodegradation.
Deng Y, Xu M, Jiang X, Wang J, Tremblay PL, Zhang T. Deng Y, et al. Environ Res. 2023 Jan 1;216(Pt 4):114808. doi: 10.1016/j.envres.2022.114808. Epub 2022 Nov 13. Environ Res. 2023. PMID: 36379237
Crystal plane regulation, defect engineering, and element doping can effectively solve the problems of large band gaps, poor light absorption, and fast recombination of BiOCl. In this work, iodine-doped BiOCl (I/BiOCl) nanowafers with abundant (110) crystal planes a …
Crystal plane regulation, defect engineering, and element doping can effectively solve the problems of large band gaps, poor light ab …
Timescales for pluton growth, magma-chamber formation and super-eruptions.
van Zalinge ME, Mark DF, Sparks RSJ, Tremblay MM, Keller CB, Cooper FJ, Rust A. van Zalinge ME, et al. Nature. 2022 Aug;608(7921):87-92. doi: 10.1038/s41586-022-04921-9. Epub 2022 Aug 3. Nature. 2022. PMID: 35922502
Ages of inherited zircons and sanidines from four Miocene ignimbrites in the Central Andes indicate a gap of 4.6 Myr between initiation of pluton emplacement and onset of super-eruptions, with a 1-Myr cyclicity. We show that inherited zircons and sanidine crystals were sto …
Ages of inherited zircons and sanidines from four Miocene ignimbrites in the Central Andes indicate a gap of 4.6 Myr between initiation of p …
Of blood, brains and bacteria, the Amt/Rh transporter family: emerging role of Amt as a unique microbial sensor.
Tremblay PL, Hallenbeck PC. Tremblay PL, et al. Mol Microbiol. 2009 Jan;71(1):12-22. doi: 10.1111/j.1365-2958.2008.06514.x. Epub 2008 Nov 5. Mol Microbiol. 2009. PMID: 19007411 Free article. Review.
At least for bacterial Amt proteins, the model emerging from computational, X-ray crystal and mutational analysis is that NH(4)(+) is deprotonated at the exterior, conducted through the membrane as NH(3), and reprotonated at the cytoplasmic interface. ...
At least for bacterial Amt proteins, the model emerging from computational, X-ray crystal and mutational analysis is that NH(4)(+) is …
Structural enzymology using X-ray free electron lasers.
Kupitz C, Olmos JL Jr, Holl M, Tremblay L, Pande K, Pandey S, Oberthür D, Hunter M, Liang M, Aquila A, Tenboer J, Calvey G, Katz A, Chen Y, Wiedorn MO, Knoska J, Meents A, Majriani V, Norwood T, Poudyal I, Grant T, Miller MD, Xu W, Tolstikova A, Morgan A, Metz M, Martin-Garcia JM, Zook JD, Roy-Chowdhury S, Coe J, Nagaratnam N, Meza D, Fromme R, Basu S, Frank M, White T, Barty A, Bajt S, Yefanov O, Chapman HN, Zatsepin N, Nelson G, Weierstall U, Spence J, Schwander P, Pollack L, Fromme P, Ourmazd A, Phillips GN Jr, Schmidt M. Kupitz C, et al. Struct Dyn. 2016 Dec 15;4(4):044003. doi: 10.1063/1.4972069. eCollection 2017 Jul. Struct Dyn. 2016. PMID: 28083542 Free PMC article.
Mix-and-inject serial crystallography (MISC) is a technique designed to image enzyme catalyzed reactions in which small protein crystals are mixed with a substrate just prior to being probed by an X-ray pulse. ...
Mix-and-inject serial crystallography (MISC) is a technique designed to image enzyme catalyzed reactions in which small protein crystals …
Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode.
Veesler D, Dreier B, Blangy S, Lichière J, Tremblay D, Moineau S, Spinelli S, Tegoni M, Plückthun A, Campanacci V, Cambillau C. Veesler D, et al. J Biol Chem. 2009 Oct 30;284(44):30718-26. doi: 10.1074/jbc.M109.037812. Epub 2009 Sep 9. J Biol Chem. 2009. PMID: 19740746 Free PMC article.
The three selected DARPins display high specificity and affinity in the low nanomolar range and bind with a stoichiometry of one DARPin per BppL trimer. The crystal structure of a DARPin complexed with the RBP was solved at 2.1 A resolution. ...This study provides proof of …
The three selected DARPins display high specificity and affinity in the low nanomolar range and bind with a stoichiometry of one DARPin per …
LassoHTP: A High-Throughput Computational Tool for Lasso Peptide Structure Construction and Modeling.
Juarez RJ, Jiang Y, Tremblay M, Shao Q, Link AJ, Yang ZJ. Juarez RJ, et al. J Chem Inf Model. 2023 Jan 23;63(2):522-530. doi: 10.1021/acs.jcim.2c00945. Epub 2023 Jan 3. J Chem Inf Model. 2023. PMID: 36594886 Free PMC article.
For benchmarking, we calculated the root mean square deviation (RMSD) of these ensembles with reference to their experimental crystal or NMR PDB structures; we also compared these RMSD values against those of the MD ensembles that are initiated from the PDB structures. ...
For benchmarking, we calculated the root mean square deviation (RMSD) of these ensembles with reference to their experimental crystal …
60 results