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Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation.
Young S, Schiffer C, Wagner A, Patz J, Potapenko A, Herrmann L, Nordhoff V, Pock T, Krallmann C, Stallmeyer B, Röpke A, Kierzek M, Biagioni C, Wang T, Haalck L, Deuster D, Hansen JN, Wachten D, Risse B, Behre HM, Schlatt S, Kliesch S, Tüttelmann F, Brenker C, Strünker T. Young S, et al. Among authors: biagioni c. J Clin Invest. 2024 Jan 2;134(1):e173564. doi: 10.1172/JCI173564. J Clin Invest. 2024. PMID: 38165034 Free PMC article.
The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn2+ on CatSper Ca2+ Channels in Human Sperm.
Jeschke JK, Biagioni C, Schierling T, Wagner IV, Börgel F, Schepmann D, Schüring A, Kulle AE, Holterhus PM, von Wolff M, Wünsch B, Nordhoff V, Strünker T, Brenker C. Jeschke JK, et al. Among authors: biagioni c. Front Cell Dev Biol. 2021 Jul 26;9:699554. doi: 10.3389/fcell.2021.699554. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34381781 Free PMC article.