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2022 | 5 |
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Page 1
Gain- and Loss-of-Function CFTR Alleles Are Associated with COVID-19 Clinical Outcomes.
Cells. 2022 Dec 16;11(24):4096. doi: 10.3390/cells11244096.
Cells. 2022.
PMID: 36552859
Free PMC article.
Rescue by elexacaftor-tezacaftor-ivacaftor of the G1244E cystic fibrosis mutation's stability and gating defects are dependent on cell background.
Tomati V, Costa S, Capurro V, Pesce E, Pastorino C, Lena M, Sondo E, Di Duca M, Cresta F, Cristadoro S, Zara F, Galietta LJV, Bocciardi R, Castellani C, Lucanto MC, Pedemonte N.
Tomati V, et al. Among authors: pastorino c.
J Cyst Fibros. 2023 May;22(3):525-537. doi: 10.1016/j.jcf.2022.12.005. Epub 2022 Dec 19.
J Cyst Fibros. 2023.
PMID: 36543707
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Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators.
Terlizzi V, Pesce E, Capurro V, Tomati V, Lena M, Pastorino C, Bocciardi R, Zara F, Centrone C, Taccetti G, Castellani C, Pedemonte N.
Terlizzi V, et al. Among authors: pastorino c.
Int J Mol Sci. 2023 Mar 31;24(7):6576. doi: 10.3390/ijms24076576.
Int J Mol Sci. 2023.
PMID: 37047546
Free PMC article.
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Targeting of Ubiquitin E3 Ligase RNF5 as a Novel Therapeutic Strategy in Neuroectodermal Tumors.
Principi E, Sondo E, Bianchi G, Ravera S, Morini M, Tomati V, Pastorino C, Zara F, Bruno C, Eva A, Pedemonte N, Raffaghello L.
Principi E, et al. Among authors: pastorino c.
Cancers (Basel). 2022 Apr 1;14(7):1802. doi: 10.3390/cancers14071802.
Cancers (Basel). 2022.
PMID: 35406574
Free PMC article.
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Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment.
Capurro V, Tomati V, Sondo E, Renda M, Borrelli A, Pastorino C, Guidone D, Venturini A, Giraudo A, Mandrup Bertozzi S, Musante I, Bertozzi F, Bandiera T, Zara F, Galietta LJV, Pedemonte N.
Capurro V, et al. Among authors: pastorino c.
Int J Mol Sci. 2021 May 17;22(10):5262. doi: 10.3390/ijms22105262.
Int J Mol Sci. 2021.
PMID: 34067708
Free PMC article.
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Journey on VX-809-Based Hybrid Derivatives towards Drug-like F508del-CFTR Correctors: From Molecular Modeling to Chemical Synthesis and Biological Assays.
Parodi A, Righetti G, Pesce E, Salis A, Tomati V, Pastorino C, Tasso B, Benvenuti M, Damonte G, Pedemonte N, Cichero E, Millo E.
Parodi A, et al. Among authors: pastorino c.
Pharmaceuticals (Basel). 2022 Feb 23;15(3):274. doi: 10.3390/ph15030274.
Pharmaceuticals (Basel). 2022.
PMID: 35337072
Free PMC article.
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The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs.
Sondo E, Cresta F, Pastorino C, Tomati V, Capurro V, Pesce E, Lena M, Iacomino M, Baffico AM, Coviello D, Bandiera T, Zara F, Galietta LJV, Bocciardi R, Castellani C, Pedemonte N.
Sondo E, et al. Among authors: pastorino c.
Int J Mol Sci. 2022 Mar 15;23(6):3175. doi: 10.3390/ijms23063175.
Int J Mol Sci. 2022.
PMID: 35328596
Free PMC article.
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