Exploring the effect of chirality on the therapeutic potential of N-alkyl-deoxyiminosugars: anti-inflammatory response to Pseudomonas aeruginosa infections for application in CF lung disease.
De Fenza M, D'Alonzo D, Esposito A, Munari S, Loberto N, Santangelo A, Lampronti I, Tamanini A, Rossi A, Ranucci S, De Fino I, Bragonzi A, Aureli M, Bassi R, Tironi M, Lippi G, Gambari R, Cabrini G, Palumbo G, Dechecchi MC, Guaragna A.
De Fenza M, et al.
Eur J Med Chem. 2019 Aug 1;175:63-71. doi: 10.1016/j.ejmech.2019.04.061. Epub 2019 Apr 25.
Eur J Med Chem. 2019.
PMID: 31075609
Free article.
In the frame of a research program aimed to explore the relationship between chirality of iminosugars and their therapeutic potential, herein we report the synthesis of N-akyl l-deoxyiminosugars and the evaluation of the anti-inflammatory properties of selected candidates …
In the frame of a research program aimed to explore the relationship between chirality of iminosugars and their therapeutic potential …