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2020 1
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2023 1
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USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer.
Maier CR, Hartmann O, Prieto-Garcia C, Al-Shami KM, Schlicker L, Vogel FCE, Haid S, Klann K, Buck V, Münch C, Schmitz W, Einig E, Krenz B, Calzado MA, Eilers M, Popov N, Rosenfeldt MT, Diefenbacher ME, Schulze A. Maier CR, et al. Among authors: prieto garcia c. Cell Death Differ. 2023 Jul;30(7):1710-1725. doi: 10.1038/s41418-023-01173-6. Epub 2023 May 18. Cell Death Differ. 2023. PMID: 37202505 Free PMC article.
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2.
Oo JA, Pálfi K, Warwick T, Wittig I, Prieto-Garcia C, Matkovic V, Tomašković I, Boos F, Izquierdo Ponce J, Teichmann T, Petriukov K, Haydar S, Maegdefessel L, Wu Z, Pham MD, Krishnan J, Baker AH, Günther S, Ulrich HD, Dikic I, Leisegang MS, Brandes RP. Oo JA, et al. Among authors: prieto garcia c. Cell Rep. 2022 Nov 15;41(7):111670. doi: 10.1016/j.celrep.2022.111670. Cell Rep. 2022. PMID: 36384122 Free PMC article.
Minimized combinatorial CRISPR screens identify genetic interactions in autophagy.
Diehl V, Wegner M, Grumati P, Husnjak K, Schaubeck S, Gubas A, Shah VJ, Polat IH, Langschied F, Prieto-Garcia C, Müller K, Kalousi A, Ebersberger I, Brandts CH, Dikic I, Kaulich M. Diehl V, et al. Among authors: prieto garcia c. Nucleic Acids Res. 2021 Jun 4;49(10):5684-5704. doi: 10.1093/nar/gkab309. Nucleic Acids Res. 2021. PMID: 33956155 Free PMC article.
PTEN mutant non-small cell lung cancer require ATM to suppress pro-apoptotic signalling and evade radiotherapy.
Fischer T, Hartmann O, Reissland M, Prieto-Garcia C, Klann K, Pahor N, Schülein-Völk C, Baluapuri A, Polat B, Abazari A, Gerhard-Hartmann E, Kopp HG, Essmann F, Rosenfeldt M, Münch C, Flentje M, Diefenbacher ME. Fischer T, et al. Among authors: prieto garcia c. Cell Biosci. 2022 Apr 27;12(1):50. doi: 10.1186/s13578-022-00778-7. Cell Biosci. 2022. PMID: 35477555 Free PMC article.
Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells.
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Fischer T, Walz S, Schülein-Völk C, Eilers U, Ade CP, Calzado MA, Orian A, Maric HM, Münch C, Rosenfeldt M, Eilers M, Diefenbacher ME. Prieto-Garcia C, et al. EMBO Mol Med. 2020 Apr 7;12(4):e11101. doi: 10.15252/emmm.201911101. Epub 2020 Mar 4. EMBO Mol Med. 2020. PMID: 32128997 Free PMC article.
USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Bozkurt S, Pahor N, Fuss C, Schirbel A, Schülein-Völk C, Buchberger A, Calzado Canale MA, Rosenfeldt M, Dikic I, Münch C, Diefenbacher ME. Prieto-Garcia C, et al. Mol Oncol. 2022 Sep;16(17):3082-3106. doi: 10.1002/1878-0261.13217. Epub 2022 Apr 30. Mol Oncol. 2022. PMID: 35364627 Free PMC article.
Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease.
Hartmann O, Reissland M, Maier CR, Fischer T, Prieto-Garcia C, Baluapuri A, Schwarz J, Schmitz W, Garrido-Rodriguez M, Pahor N, Davies CC, Bassermann F, Orian A, Wolf E, Schulze A, Calzado MA, Rosenfeldt MT, Diefenbacher ME. Hartmann O, et al. Among authors: prieto garcia c. Front Cell Dev Biol. 2021 Mar 2;9:641618. doi: 10.3389/fcell.2021.641618. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33738287 Free PMC article.