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Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts.
Nat Commun. 2015 Sep 9;6:8214. doi: 10.1038/ncomms9214.
Nat Commun. 2015.
PMID: 26351258
Free PMC article.
Loop and backbone modifications of peptide nucleic acid improve g-quadruplex binding selectivity.
Lusvarghi S, Murphy CT, Roy S, Tanious FA, Sacui I, Wilson WD, Ly DH, Armitage BA.
Lusvarghi S, et al. Among authors: murphy ct.
J Am Chem Soc. 2009 Dec 30;131(51):18415-24. doi: 10.1021/ja907250j.
J Am Chem Soc. 2009.
PMID: 19947597
Free PMC article.
Item in Clipboard
DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation.
Lormand JD, Buncher N, Murphy CT, Kaur P, Lee MY, Burgers P, Wang H, Kunkel TA, Opresko PL.
Lormand JD, et al. Among authors: murphy ct.
Nucleic Acids Res. 2013 Dec;41(22):10323-33. doi: 10.1093/nar/gkt813. Epub 2013 Sep 13.
Nucleic Acids Res. 2013.
PMID: 24038470
Free PMC article.
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γPNA FRET Pair Miniprobes for Quantitative Fluorescent In Situ Hybridization to Telomeric DNA in Cells and Tissue.
Orenstein A, Berlyoung AS, Rastede EE, Pham HH, Fouquerel E, Murphy CT, Leibowitz BJ, Yu J, Srivastava T, Armitage BA, Opresko PL.
Orenstein A, et al. Among authors: murphy ct.
Molecules. 2017 Dec 2;22(12):2117. doi: 10.3390/molecules22122117.
Molecules. 2017.
PMID: 29207465
Free PMC article.
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Hybridization of G-quadruplex-forming peptide nucleic acids to guanine-rich DNA templates inhibits DNA polymerase η extension.
Murphy CT, Gupta A, Armitage BA, Opresko PL.
Murphy CT, et al.
Biochemistry. 2014 Aug 19;53(32):5315-22. doi: 10.1021/bi5006859. Epub 2014 Aug 5.
Biochemistry. 2014.
PMID: 25068499
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Kinetic discrimination in recognition of DNA quadruplex targets by guanine-rich heteroquadruplex-forming PNA probes.
Roy S, Zanotti KJ, Murphy CT, Tanious FA, Wilson WD, Ly DH, Armitage BA.
Roy S, et al. Among authors: murphy ct.
Chem Commun (Camb). 2011 Aug 14;47(30):8524-6. doi: 10.1039/c1cc12805a. Epub 2011 Jun 30.
Chem Commun (Camb). 2011.
PMID: 21717030
Free PMC article.
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Cooperative hybridization of γPNA miniprobes to a repeating sequence motif and application to telomere analysis.
Pham HH, Murphy CT, Sureshkumar G, Ly DH, Opresko PL, Armitage BA.
Pham HH, et al. Among authors: murphy ct.
Org Biomol Chem. 2014 Oct 7;12(37):7345-7354. doi: 10.1039/c4ob00953c.
Org Biomol Chem. 2014.
PMID: 25115693
Free PMC article.
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