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Page 1
Characterization of N-Terminal Glutamate Cyclization in Monoclonal Antibody and Bispecific Antibody Using Charge Heterogeneity Assays and Hydrophobic Interaction Chromatography.
J Pharm Sci. 2022 Feb;111(2):335-344. doi: 10.1016/j.xphs.2021.09.006. Epub 2021 Sep 10.
J Pharm Sci. 2022.
PMID: 34516988
Free article.
Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis.
Cao M, De Mel N, Jiao Y, Howard J, Parthemore C, Korman S, Thompson C, Wendeler M, Liu D.
Cao M, et al. Among authors: parthemore c.
MAbs. 2019 Aug/Sep;11(6):1064-1076. doi: 10.1080/19420862.2019.1624127. Epub 2019 Jun 14.
MAbs. 2019.
PMID: 31198090
Free PMC article.
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Characterization and Monitoring of a Novel Light-heavy-light Chain Mispair in a Therapeutic Bispecific Antibody.
Cao M, Parthemore C, Jiao Y, Korman S, Aspelund M, Hunter A, Kilby G, Chen X.
Cao M, et al. Among authors: parthemore c.
J Pharm Sci. 2021 Aug;110(8):2904-2915. doi: 10.1016/j.xphs.2021.04.010. Epub 2021 Apr 21.
J Pharm Sci. 2021.
PMID: 33894207
Free article.
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Atypical Asparagine Deamidation of NW Motif Significantly Attenuates the Biological Activities of an Antibody Drug Conjugate.
Cao M, Hussmann GP, Tao Y, O'Connor E, Parthemore C, Zhang-Hulsey D, Liu D, Jiao Y, Mel N, Prophet M, Korman S, Sonawane J, Grigoriadou C, Huang Y, Umlauf S, Chen X.
Cao M, et al. Among authors: parthemore c.
Antibodies (Basel). 2023 Oct 24;12(4):68. doi: 10.3390/antib12040068.
Antibodies (Basel). 2023.
PMID: 37987246
Free PMC article.
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Identification of a CE-SDS shoulder peak as disulfide-linked fragments from common CH2 cleavages in IgGs and IgG-like bispecific antibodies.
Cao M, Jiao Y, Parthemore C, Korman S, Ma J, Hunter A, Kilby G, Chen X.
Cao M, et al. Among authors: parthemore c.
MAbs. 2021 Jan-Dec;13(1):1981806. doi: 10.1080/19420862.2021.1981806.
MAbs. 2021.
PMID: 34719342
Free PMC article.
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