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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1923 1
1971 1
1972 1
1975 1
1983 4
1984 2
1985 5
1986 2
1987 1
1988 7
1989 1
1990 13
1991 5
1992 7
1993 6
1994 9
1995 11
1996 14
1997 14
1998 14
1999 17
2000 25
2001 20
2002 25
2003 29
2004 36
2005 33
2006 51
2007 45
2008 52
2009 48
2010 42
2011 60
2012 65
2013 69
2014 73
2015 88
2016 87
2017 73
2018 121
2019 95
2020 120
2021 125
2022 130
2023 126
2024 38

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1,680 results

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Page 1
Showing results for clonal tree
Search for Conal True instead (3 results)
Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics.
Jun SH, Toosi H, Mold J, Engblom C, Chen X, O'Flanagan C, Hagemann-Jensen M, Sandberg R, Aparicio S, Hartman J, Roth A, Lagergren J. Jun SH, et al. Nat Commun. 2023 Feb 22;14(1):982. doi: 10.1038/s41467-023-36202-y. Nat Commun. 2023. PMID: 36813776 Free PMC article.
We present PhylEx that integrates bulk genomics data with co-occurrences of mutations from single-cell RNA sequencing data to reconstruct high-fidelity clonal trees. We evaluate PhylEx on synthetic and well-characterized high-grade serous ovarian cancer cell line da …
We present PhylEx that integrates bulk genomics data with co-occurrences of mutations from single-cell RNA sequencing data to reconstruct hi …
Clonal analysis of lineage fate in native haematopoiesis.
Rodriguez-Fraticelli AE, Wolock SL, Weinreb CS, Panero R, Patel SH, Jankovic M, Sun J, Calogero RA, Klein AM, Camargo FD. Rodriguez-Fraticelli AE, et al. Nature. 2018 Jan 11;553(7687):212-216. doi: 10.1038/nature25168. Epub 2018 Jan 3. Nature. 2018. PMID: 29323290 Free PMC article.
Here we use transposon tagging to clonally trace the fates of progenitors and stem cells in unperturbed haematopoiesis. Our results describe a distinct clonal roadmap in which the megakaryocyte lineage arises largely independently of other haematopoietic fates. ...
Here we use transposon tagging to clonally trace the fates of progenitors and stem cells in unperturbed haematopoiesis. Our results d …
TRIBAL: Tree Inference of B cell Clonal Lineages.
Weber LL, Reiman D, Roddur MS, Qi Y, El-Kebir M, Khan AA. Weber LL, et al. bioRxiv [Preprint]. 2023 Nov 27:2023.11.27.568874. doi: 10.1101/2023.11.27.568874. bioRxiv. 2023. PMID: 38076836 Free PMC article. Preprint.
We introduce a new method, TRIBAL, which aims to infer the evolutionary history of clonally related B cells from scRNA-seq data. The key insight of TRIBAL is that inclusion of isotype data into the B cell lineage inference problem is valuable for reducing phylogenetic unce …
We introduce a new method, TRIBAL, which aims to infer the evolutionary history of clonally related B cells from scRNA-seq data. The …
Conifer: clonal tree inference for tumor heterogeneity with single-cell and bulk sequencing data.
Baghaarabani L, Goliaei S, Foroughmand-Araabi MH, Shariatpanahi SP, Goliaei B. Baghaarabani L, et al. BMC Bioinformatics. 2021 Aug 30;22(1):416. doi: 10.1186/s12859-021-04338-7. BMC Bioinformatics. 2021. PMID: 34461827 Free PMC article.
BACKGROUND: Genetic heterogeneity of a cancer tumor that develops during clonal evolution is one of the reasons for cancer treatment failure, by increasing the chance of drug resistance. ...It is proven that the accuracy of clone identification and clonal tree …
BACKGROUND: Genetic heterogeneity of a cancer tumor that develops during clonal evolution is one of the reasons for cancer treatment …
Clonal production of tea tree oil high in terpinen-4-ol for use in formulations for the treatment of thrush.
Williams LR. Williams LR. Complement Ther Nurs Midwifery. 1998 Oct;4(5):133-6. doi: 10.1016/s1353-6117(98)80086-3. Complement Ther Nurs Midwifery. 1998. PMID: 9830943 Review.
A programme of evaluation and selection of superior trees has led to the vegetative propagation of highly productive clones which produce tea tree oil high in terpinen-4-ol. ...
A programme of evaluation and selection of superior trees has led to the vegetative propagation of highly productive clones which pro …
Phertilizer: Growing a clonal tree from ultra-low coverage single-cell DNA sequencing of tumors.
Weber LL, Zhang C, Ochoa I, El-Kebir M. Weber LL, et al. PLoS Comput Biol. 2023 Oct 11;19(10):e1011544. doi: 10.1371/journal.pcbi.1011544. eCollection 2023 Oct. PLoS Comput Biol. 2023. PMID: 37819942 Free PMC article.
In order to maximize the utility of increasingly available ultra-low coverage scDNA-seq data and obtain a comprehensive understanding of tumor evolution, it is important to also analyze the evolution of SNVs from the same set of tumor cells. We present Phertilizer, a method to in …
In order to maximize the utility of increasingly available ultra-low coverage scDNA-seq data and obtain a comprehensive understanding of tum …
A scalable model for simulating multi-round antibody evolution and benchmarking of clonal tree reconstruction methods.
Zhang C, Bzikadze AV, Safonova Y, Mirarab S. Zhang C, et al. Front Immunol. 2022 Dec 6;13:1014439. doi: 10.3389/fimmu.2022.1014439. eCollection 2022. Front Immunol. 2022. PMID: 36618367 Free PMC article.
In fact, several clonal tree reconstruction methods have been developed to fix supposed shortcomings of phylogenetic methods. ...In this paper, we propose a model for modeling B cell clonal lineage evolution and use this model to benchmark several existing …
In fact, several clonal tree reconstruction methods have been developed to fix supposed shortcomings of phylogenetic methods. …
A multi-labeled tree dissimilarity measure for comparing "clonal trees" of tumor progression.
Karpov N, Malikic S, Rahman MK, Sahinalp SC. Karpov N, et al. Algorithms Mol Biol. 2019 Jul 27;14:17. doi: 10.1186/s13015-019-0152-9. eCollection 2019. Algorithms Mol Biol. 2019. PMID: 31372179 Free PMC article.
Given two clonal trees, our multi-labeled tree dissimilarity (MLTD) measure is defined as the minimum number of mutation/label deletions, (empty) leaf deletions, and vertex (clonal) expansions, applied in any order, to convert each of the two trees …
Given two clonal trees, our multi-labeled tree dissimilarity (MLTD) measure is defined as the minimum number of mutatio …
Forest tree biotechnology.
Merkle SA, Dean JF. Merkle SA, et al. Curr Opin Biotechnol. 2000 Jun;11(3):298-302. doi: 10.1016/s0958-1669(00)00099-9. Curr Opin Biotechnol. 2000. PMID: 10851143 Review.
The past year has seen the fruits of biotechnological manipulation of forest trees approach commercial application. Advances in somatic embryogenesis have brought mass clonal propagation of the top commercial trees closer to reality, and efficient gene transf …
The past year has seen the fruits of biotechnological manipulation of forest trees approach commercial application. Advances in somat …
Effect of clonal testing on the efficiency of genomic evaluation in forest tree breeding.
Stejskal J, Klápště J, Čepl J, El-Kassaby YA, Lstibůrek M. Stejskal J, et al. Sci Rep. 2022 Feb 22;12(1):3033. doi: 10.1038/s41598-022-06952-8. Sci Rep. 2022. PMID: 35194102 Free PMC article.
We found that clonal replication in progeny trials boosted selection accuracy, thus providing additional genetic gains under BLUP. ...Therefore, breeding programs deploying extensive progeny testing with clonal propagation might not benefit from the deployment of ge …
We found that clonal replication in progeny trials boosted selection accuracy, thus providing additional genetic gains under BLUP. .. …
1,680 results