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Year Number of Results
2011 2
2012 1
2013 1
2014 1
2015 2
2016 1
2017 1
2018 1
2019 2
2020 1
2021 1
2022 1
2023 1
2024 0

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15 results

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Page 1
A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA-MONO/GOG-3020/ENGOT-ov45).
Monk BJ, Parkinson C, Lim MC, O'Malley DM, Oaknin A, Wilson MK, Coleman RL, Lorusso D, Bessette P, Ghamande S, Christopoulou A, Provencher D, Prendergast E, Demirkiran F, Mikheeva O, Yeku O, Chudecka-Glaz A, Schenker M, Littell RD, Safra T, Chou HH, Morgan MA, Drochýtek V, Barlin JN, Van Gorp T, Ueland F, Lindahl G, Anderson C, Collins DC, Moore K, Marme F, Westin SN, McNeish IA, Shih D, Lin KK, Goble S, Hume S, Fujiwara K, Kristeleit RS. Monk BJ, et al. J Clin Oncol. 2022 Dec 1;40(34):3952-3964. doi: 10.1200/JCO.22.01003. Epub 2022 Jun 6. J Clin Oncol. 2022. PMID: 35658487 Free PMC article. Clinical Trial.
Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies.
Coresh J, Heerspink HJL, Sang Y, Matsushita K, Arnlov J, Astor BC, Black C, Brunskill NJ, Carrero JJ, Feldman HI, Fox CS, Inker LA, Ishani A, Ito S, Jassal S, Konta T, Polkinghorne K, Romundstad S, Solbu MD, Stempniewicz N, Stengel B, Tonelli M, Umesawa M, Waikar SS, Wen CP, Wetzels JFM, Woodward M, Grams ME, Kovesdy CP, Levey AS, Gansevoort RT; Chronic Kidney Disease Prognosis Consortium and Chronic Kidney Disease Epidemiology Collaboration. Coresh J, et al. Lancet Diabetes Endocrinol. 2019 Feb;7(2):115-127. doi: 10.1016/S2213-8587(18)30313-9. Epub 2019 Jan 8. Lancet Diabetes Endocrinol. 2019. PMID: 30635225 Free PMC article.
The interplay between sex, time of day, fasting status, and their impact on cardiac mitochondrial structure, function, and dynamics.
Kane MS, Benavides GA, Osuma E, Johnson MS, Collins HE, He Y, Westbrook D, Litovsky SH, Mitra K, Chatham JC, Darley-Usmar V, Young ME, Zhang J. Kane MS, et al. Sci Rep. 2023 Dec 7;13(1):21638. doi: 10.1038/s41598-023-49018-z. Sci Rep. 2023. PMID: 38062139 Free PMC article.
We investigated whether these are influenced by time of the day (TOD), sex, and fed or fasting status, using transmission electron microscopy (EM), mitochondrial electron transport chain (ETC) activity, and mito-QC reporter mice. We observed peak mitochondrial number at ZT …
We investigated whether these are influenced by time of the day (TOD), sex, and fed or fasting status, using transmission electron microscop …
Mitochondrial fission, integrity and completion of mitophagy require separable functions of Vps13D in Drosophila neurons.
Insolera R, Lőrincz P, Wishnie AJ, Juhász G, Collins CA. Insolera R, et al. PLoS Genet. 2021 Aug 12;17(8):e1009731. doi: 10.1371/journal.pgen.1009731. eCollection 2021 Aug. PLoS Genet. 2021. PMID: 34383748 Free PMC article.
Reporter assays combined with genetic studies imply that mitophagy both initiates and is completed in Drp1 impaired neurons, but fails to complete in Vps13D impaired neurons, which accumulate compromised mitochondria within stalled mito-phagophores. Our findings imply that …
Reporter assays combined with genetic studies imply that mitophagy both initiates and is completed in Drp1 impaired neurons, but fails to co …
Phenotypic Variation in Mitochondria-Related Performance Traits Across New Zealand Snail Populations.
Greimann ES, Ward SF, Woodell JD, Hennessey S, Kline MR, Moreno JA, Peters M, Cruise JL, Montooth KL, Neiman M, Sharbrough J. Greimann ES, et al. Integr Comp Biol. 2020 Aug 1;60(2):275-287. doi: 10.1093/icb/icaa066. Integr Comp Biol. 2020. PMID: 32589742
Mitochondrial function is encoded by genes in two distinct and separately inherited genomes-the mitochondrial genome and the nuclear genome-and selection is expected to maintain functional mito-nuclear interactions. The documented high levels of polymorphism in genes invol …
Mitochondrial function is encoded by genes in two distinct and separately inherited genomes-the mitochondrial genome and the nuclear genome- …
Common data elements for clinical research in mitochondrial disease: a National Institute for Neurological Disorders and Stroke project.
Karaa A, Rahman S, Lombès A, Yu-Wai-Man P, Sheikh MK, Alai-Hansen S, Cohen BH, Dimmock D, Emrick L, Falk MJ, McCormack S, Mirsky D, Moore T, Parikh S, Shoffner J, Taivassalo T, Tarnopolsky M, Tein I, Odenkirchen JC, Goldstein A; Mito Working Group Member Participants:. Karaa A, et al. J Inherit Metab Dis. 2017 May;40(3):403-414. doi: 10.1007/s10545-017-0035-5. Epub 2017 Mar 16. J Inherit Metab Dis. 2017. PMID: 28303425 Free PMC article.
CDEs have been created for several neurological diseases; the aim of this project was to develop CDEs specifically curated for mitochondrial disease (Mito) to enhance clinical research. METHODS: Nine working groups (WGs), composed of international mitochondrial disease exp …
CDEs have been created for several neurological diseases; the aim of this project was to develop CDEs specifically curated for mitochondrial …
Assessment of mitochondrial biogenesis and mTORC1 signaling during chronic rapamycin feeding in male and female mice.
Drake JC, Peelor FF 3rd, Biela LM, Watkins MK, Miller RA, Hamilton KL, Miller BF. Drake JC, et al. J Gerontol A Biol Sci Med Sci. 2013 Dec;68(12):1493-501. doi: 10.1093/gerona/glt047. Epub 2013 May 8. J Gerontol A Biol Sci Med Sci. 2013. PMID: 23657975 Free PMC article.
Protein synthesis in mixed, cytosolic (cyto), and mitochondrial (mito) fractions and DNA synthesis and mTORC1 signaling were determined in skeletal muscle, heart, and liver. In both sexes, mito protein synthesis was maintained in skeletal muscle from Rap despite dec …
Protein synthesis in mixed, cytosolic (cyto), and mitochondrial (mito) fractions and DNA synthesis and mTORC1 signaling were determin …
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria.
Hoppins S, Collins SR, Cassidy-Stone A, Hummel E, Devay RM, Lackner LL, Westermann B, Schuldiner M, Weissman JS, Nunnari J. Hoppins S, et al. J Cell Biol. 2011 Oct 17;195(2):323-40. doi: 10.1083/jcb.201107053. Epub 2011 Oct 10. J Cell Biol. 2011. PMID: 21987634 Free PMC article.
To broadly explore mitochondrial structure and function as well as the communication of mitochondria with other cellular pathways, we constructed a quantitative, high-density genetic interaction map (the MITO-MAP) in Saccharomyces cerevisiae. The MITO-MAP provides a …
To broadly explore mitochondrial structure and function as well as the communication of mitochondria with other cellular pathways, we constr …
Assessment of protein synthesis in highly aerobic canine species at the onset and during exercise training.
Miller BF, Ehrlicher SE, Drake JC, Peelor FF 3rd, Biela LM, Pratt-Phillips S, Davis M, Hamilton KL. Miller BF, et al. J Appl Physiol (1985). 2015 Apr 1;118(7):811-7. doi: 10.1152/japplphysiol.00982.2014. Epub 2015 Jan 22. J Appl Physiol (1985). 2015. PMID: 25614602 Free PMC article.
Both groups of dogs had very high rates of skeletal muscle protein synthesis in the sedentary state [Alaskan Huskies: Mixed = 2.28 0.12, cytoplasmic (Cyto) = 2.91 0.10, and mitochondrial (Mito) = 2.62 0.07; Labrador Retrievers: Mixed = 3.88 0.37, Cyto = 3.85 0.06, and M
Both groups of dogs had very high rates of skeletal muscle protein synthesis in the sedentary state [Alaskan Huskies: Mixed = 2.28 0.12, cyt …
15 results