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2020 1
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Page 1
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.
Previti S, Ettari R, Calcaterra E, Di Chio C, Ravichandran R, Zimmer C, Hammerschmidt S, Wagner A, Bogacz M, Cosconati S, Schirmeister T, Zappalà M. Previti S, et al. Among authors: zimmer c. ACS Med Chem Lett. 2022 Jun 30;13(7):1083-1090. doi: 10.1021/acsmedchemlett.2c00084. eCollection 2022 Jul 14. ACS Med Chem Lett. 2022. PMID: 35859868 Free PMC article.
Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2.
Welker A, Kersten C, Müller C, Madhugiri R, Zimmer C, Müller P, Zimmermann R, Hammerschmidt S, Maus H, Ziebuhr J, Sotriffer C, Schirmeister T. Welker A, et al. Among authors: zimmer c. ChemMedChem. 2021 Jan 19;16(2):340-354. doi: 10.1002/cmdc.202000548. Epub 2020 Oct 16. ChemMedChem. 2021. PMID: 32930481 Free PMC article.
Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies.
Jung S, Fuchs N, Johe P, Wagner A, Diehl E, Yuliani T, Zimmer C, Barthels F, Zimmermann RA, Klein P, Waigel W, Meyr J, Opatz T, Tenzer S, Distler U, Räder HJ, Kersten C, Engels B, Hellmich UA, Klein J, Schirmeister T. Jung S, et al. Among authors: zimmer c. J Med Chem. 2021 Aug 26;64(16):12322-12358. doi: 10.1021/acs.jmedchem.1c01002. Epub 2021 Aug 11. J Med Chem. 2021. PMID: 34378914
Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors-A Comprehensive Reactivity and Selectivity Study.
Müller P, Meta M, Meidner JL, Schwickert M, Meyr J, Schwickert K, Kersten C, Zimmer C, Hammerschmidt SJ, Frey A, Lahu A, de la Hoz-Rodríguez S, Agost-Beltrán L, Rodríguez S, Diemer K, Neumann W, Gonzàlez FV, Engels B, Schirmeister T. Müller P, et al. Among authors: zimmer c. Int J Mol Sci. 2023 Apr 13;24(8):7226. doi: 10.3390/ijms24087226. Int J Mol Sci. 2023. PMID: 37108388 Free PMC article.
Influence of amino acid size at the P3 position of N-Cbz-tripeptide Michael acceptors targeting falcipain-2 and rhodesain for the treatment of malaria and human african trypanosomiasis.
Previti S, Ettari R, Di Chio C, Legac J, Bogacz M, Zimmer C, Schirmeister T, Rosenthal PJ, Zappalà M. Previti S, et al. Among authors: zimmer c. Bioorg Chem. 2023 Aug;137:106587. doi: 10.1016/j.bioorg.2023.106587. Epub 2023 May 4. Bioorg Chem. 2023. PMID: 37163812 Free article.
14 results