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Showing results for clare small
Search for Claire Seall instead (1 results)
Dexamethasone in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17. N Engl J Med. 2021. PMID: 32678530 Free PMC article. Clinical Trial.
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells.
Wang Y, Yen FS, Zhu XG, Timson RC, Weber R, Xing C, Liu Y, Allwein B, Luo H, Yeh HW, Heissel S, Unlu G, Gamazon ER, Kharas MG, Hite R, Birsoy K. Wang Y, et al. Nature. 2021 Nov;599(7883):136-140. doi: 10.1038/s41586-021-04025-w. Epub 2021 Oct 27. Nature. 2021. PMID: 34707288 Free PMC article.
Glutathione (GSH) is a small-molecule thiol that is abundant in all eukaryotes and has key roles in oxidative metabolism(1). ...
Glutathione (GSH) is a small-molecule thiol that is abundant in all eukaryotes and has key roles in oxidative metabolism(1). ...
Small Molecule Drug Discovery for Neglected Tropical Snakebite.
Clare RH, Hall SR, Patel RN, Casewell NR. Clare RH, et al. Trends Pharmacol Sci. 2021 May;42(5):340-353. doi: 10.1016/j.tips.2021.02.005. Epub 2021 Mar 24. Trends Pharmacol Sci. 2021. PMID: 33773806 Review.
Herein we describe the challenges associated with the discovery and development of new snakebite treatments and detail the great potential of venom toxin-inhibiting small molecule drugs. We finish by highlighting successful enabling strategies applied to other NTDs that co …
Herein we describe the challenges associated with the discovery and development of new snakebite treatments and detail the great potential o …
Cognitive training for people with mild to moderate dementia.
Bahar-Fuchs A, Martyr A, Goh AM, Sabates J, Clare L. Bahar-Fuchs A, et al. Cochrane Database Syst Rev. 2019 Mar 25;3(3):CD013069. doi: 10.1002/14651858.CD013069.pub2. Cochrane Database Syst Rev. 2019. PMID: 30909318 Free PMC article.
Relative to a control condition, we found moderate-quality evidence showing a small to moderate effect of CT on our first primary outcome, composite measure of global cognition at end of treatment (standardised mean difference (SMD) 0.42, 95% confidence interval (CI) 0.23 …
Relative to a control condition, we found moderate-quality evidence showing a small to moderate effect of CT on our first primary out …
Cognitive training interventions for dementia and mild cognitive impairment in Parkinson's disease.
Orgeta V, McDonald KR, Poliakoff E, Hindle JV, Clare L, Leroi I. Orgeta V, et al. Cochrane Database Syst Rev. 2020 Feb 26;2(2):CD011961. doi: 10.1002/14651858.CD011961.pub2. Cochrane Database Syst Rev. 2020. PMID: 32101639 Free PMC article.
AUTHORS' CONCLUSIONS: This review found no evidence that people with PD-MCI or PDD who receive cognitive training for four to eight weeks experience any important cognitive improvements at the end of training. However, this conclusion was based on a small number of studies …
AUTHORS' CONCLUSIONS: This review found no evidence that people with PD-MCI or PDD who receive cognitive training for four to eight weeks ex …
Antibody tests for identification of current and past infection with SARS-CoV-2.
Fox T, Geppert J, Dinnes J, Scandrett K, Bigio J, Sulis G, Hettiarachchi D, Mathangasinghe Y, Weeratunga P, Wickramasinghe D, Bergman H, Buckley BS, Probyn K, Sguassero Y, Davenport C, Cunningham J, Dittrich S, Emperador D, Hooft L, Leeflang MM, McInnes MD, Spijker R, Struyf T, Van den Bruel A, Verbakel JY, Takwoingi Y, Taylor-Phillips S, Deeks JJ; Cochrane COVID-19 Diagnostic Test Accuracy Group. Fox T, et al. Cochrane Database Syst Rev. 2022 Nov 17;11(11):CD013652. doi: 10.1002/14651858.CD013652.pub2. Cochrane Database Syst Rev. 2022. PMID: 36394900 Free PMC article. Review.
Studies must have provided data for sensitivity, that could be allocated to a predefined time period after onset of symptoms, or after a positive RT-PCR test. Small studies with fewer than 25 SARS-CoV-2 infection cases were excluded. ...For tests that were evaluated in 200 …
Studies must have provided data for sensitivity, that could be allocated to a predefined time period after onset of symptoms, or after a pos …
Goal-oriented cognitive rehabilitation for early-stage Alzheimer's and related dementias: the GREAT RCT.
Clare L, Kudlicka A, Oyebode JR, Jones RW, Bayer A, Leroi I, Kopelman M, James IA, Culverwell A, Pool J, Brand A, Henderson C, Hoare Z, Knapp M, Morgan-Trimmer S, Burns A, Corbett A, Whitaker R, Woods B. Clare L, et al. Health Technol Assess. 2019 Mar;23(10):1-242. doi: 10.3310/hta23100. Health Technol Assess. 2019. PMID: 30879470 Free PMC article. Clinical Trial.
A therapist works with the person and the carer to identify realistic and relevant goals, plan how to tackle these and support people in achieving them. Previous small studies suggested that CR could be beneficial. METHODS: The Goal-oriented cognitive Rehabilitation in Ear …
A therapist works with the person and the carer to identify realistic and relevant goals, plan how to tackle these and support people in ach …
392 results