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Page 1
A Transversal Approach Combining In Silico, In Vitro and In Vivo Models to Describe the Metabolism of the Receptor Interacting Protein 1 Kinase Inhibitor Sibiriline.
Pelletier R, Gicquel T, Simoes Eugenio M, Ferron PJ, Morel I, Delehouzé C, Dimanche-Boitrel MT, Rousselot M, Le Daré B. Pelletier R, et al. Among authors: delehouze c. Pharmaceutics. 2022 Nov 30;14(12):2665. doi: 10.3390/pharmaceutics14122665. Pharmaceutics. 2022. PMID: 36559159 Free PMC article.
Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor.
Ahmadu AA, Delehouzé C, Haruna A, Mustapha L, Lawal BA, Udobre A, Baratte B, Triscornia C, Autret A, Robert T, Bulinski JC, Rousselot M, Simoes Eugénio M, Dimanche-Boitrel MT, Petzer JP, Legoabe LJ, Bach S. Ahmadu AA, et al. Among authors: delehouze c. Molecules. 2021 Jul 29;26(15):4599. doi: 10.3390/molecules26154599. Molecules. 2021. PMID: 34361750 Free PMC article.
Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis.
Le Cann F, Delehouzé C, Leverrier-Penna S, Filliol A, Comte A, Delalande O, Desban N, Baratte B, Gallais I, Piquet-Pellorce C, Faurez F, Bonnet M, Mettey Y, Goekjian P, Samson M, Vandenabeele P, Bach S, Dimanche-Boitrel MT. Le Cann F, et al. Among authors: delehouze c. FEBS J. 2017 Sep;284(18):3050-3068. doi: 10.1111/febs.14176. Epub 2017 Aug 11. FEBS J. 2017. PMID: 28715128 Free article.
Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1.
Moine E, Dimier-Poisson I, Enguehard-Gueiffier C, Logé C, Pénichon M, Moiré N, Delehouzé C, Foll-Josselin B, Ruchaud S, Bach S, Gueiffier A, Debierre-Grockiego F, Denevault-Sabourin C. Moine E, et al. Among authors: delehouze c. Eur J Med Chem. 2015 Nov 13;105:80-105. doi: 10.1016/j.ejmech.2015.10.004. Epub 2015 Oct 9. Eur J Med Chem. 2015. PMID: 26479029
Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.
Billot K, Coquil C, Villiers B, Josselin-Foll B, Desban N, Delehouzé C, Oumata N, Le Meur Y, Boletta A, Weimbs T, Grosch M, Witzgall R, Saunier S, Fischer E, Pontoglio M, Fautrel A, Mrug M, Wallace D, Tran PV, Trudel M, Bukanov N, Ibraghimov-Beskrovnaya O, Meijer L. Billot K, et al. Among authors: delehouze c. Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F57-F73. doi: 10.1152/ajprenal.00489.2017. Epub 2018 Mar 14. Am J Physiol Renal Physiol. 2018. PMID: 29537311 Free PMC article.
Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein Kinase-1.
Benchekroun M, Ermolenko L, Tran MQ, Vagneux A, Nedev H, Delehouzé C, Souab M, Baratte B, Josselin B, Iorga BI, Ruchaud S, Bach S, Al-Mourabit A. Benchekroun M, et al. Among authors: delehouze c. Eur J Med Chem. 2020 Sep 1;201:112337. doi: 10.1016/j.ejmech.2020.112337. Epub 2020 Jun 25. Eur J Med Chem. 2020. PMID: 32659605
11 results