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Page 1
NMR Meets Tau: Insights into Its Function and Pathology.
Lippens G, Landrieu I, Smet C, Huvent I, Gandhi NS, Gigant B, Despres C, Qi H, Lopez J. Lippens G, et al. Among authors: despres c. Biomolecules. 2016 Jun 7;6(2):28. doi: 10.3390/biom6020028. Biomolecules. 2016. PMID: 27338491 Free PMC article. Review.
Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors.
Despres C, Di J, Cantrelle FX, Li Z, Huvent I, Chambraud B, Zhao J, Chen J, Chen S, Lippens G, Zhang F, Linhardt R, Wang C, Klärner FG, Schrader T, Landrieu I, Bitan G, Smet-Nocca C. Despres C, et al. ACS Chem Biol. 2019 Jun 21;14(6):1363-1379. doi: 10.1021/acschembio.9b00325. Epub 2019 May 15. ACS Chem Biol. 2019. PMID: 31046227 Free PMC article.
Identification of the Tau phosphorylation pattern that drives its aggregation.
Despres C, Byrne C, Qi H, Cantrelle FX, Huvent I, Chambraud B, Baulieu EE, Jacquot Y, Landrieu I, Lippens G, Smet-Nocca C. Despres C, et al. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9080-9085. doi: 10.1073/pnas.1708448114. Epub 2017 Aug 7. Proc Natl Acad Sci U S A. 2017. PMID: 28784767 Free PMC article.
Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates.
Cantrelle FX, Loyens A, Trivelli X, Reimann O, Despres C, Gandhi NS, Hackenberger CPR, Landrieu I, Smet-Nocca C. Cantrelle FX, et al. Among authors: despres c. Front Mol Neurosci. 2021 Jun 17;14:661368. doi: 10.3389/fnmol.2021.661368. eCollection 2021. Front Mol Neurosci. 2021. PMID: 34220449 Free PMC article.
The Study of Posttranslational Modifications of Tau Protein by Nuclear Magnetic Resonance Spectroscopy: Phosphorylation of Tau Protein by ERK2 Recombinant Kinase and Rat Brain Extract, and Acetylation by Recombinant Creb-Binding Protein.
Qi H, Despres C, Prabakaran S, Cantrelle FX, Chambraud B, Gunawardena J, Lippens G, Smet-Nocca C, Landrieu I. Qi H, et al. Among authors: despres c. Methods Mol Biol. 2017;1523:179-213. doi: 10.1007/978-1-4939-6598-4_11. Methods Mol Biol. 2017. PMID: 27975251
Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator.
Nshanian M, Lantz C, Wongkongkathep P, Schrader T, Klärner FG, Blümke A, Despres C, Ehrmann M, Smet-Nocca C, Bitan G, Loo JA. Nshanian M, et al. Among authors: despres c. J Am Soc Mass Spectrom. 2019 Jan;30(1):16-23. doi: 10.1007/s13361-018-2027-6. Epub 2018 Jul 30. J Am Soc Mass Spectrom. 2019. PMID: 30062477 Free PMC article.