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2021 2
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Page 1
Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals.
Goikoetxea-Usandizaga N, Serrano-Maciá M, Delgado TC, Simón J, Fernández Ramos D, Barriales D, Cornide ME, Jiménez M, Pérez-Redondo M, Lachiondo-Ortega S, Rodríguez-Agudo R, Bizkarguenaga M, Zalamea JD, Pasco ST, Caballero-Díaz D, Alfano B, Bravo M, González-Recio I, Mercado-Gómez M, Gil-Pitarch C, Mabe J, Gracia-Sancho J, Abecia L, Lorenzo Ó, Martín-Sanz P, Abrescia NGA, Sabio G, Rincón M, Anguita J, Miñambres E, Martín C, Berenguer M, Fabregat I, Casado M, Peralta C, Varela-Rey M, Martínez-Chantar ML. Goikoetxea-Usandizaga N, et al. Among authors: gil pitarch c. Hepatology. 2022 Mar;75(3):550-566. doi: 10.1002/hep.32149. Epub 2021 Dec 15. Hepatology. 2022. PMID: 34510498 Free PMC article.
Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage.
González-Recio I, Simón J, Goikoetxea-Usandizaga N, Serrano-Maciá M, Mercado-Gómez M, Rodríguez-Agudo R, Lachiondo-Ortega S, Gil-Pitarch C, Fernández-Rodríguez C, Castellana D, Latasa MU, Abecia L, Anguita J, Delgado TC, Iruzubieta P, Crespo J, Hardy S, Petrov PD, Jover R, Avila MA, Martín C, Schaeper U, Tremblay ML, Dear JW, Masson S, McCain MV, Reeves HL, Andrade RJ, Lucena MI, Buccella D, Martínez-Cruz LA, Martínez-Chantar ML. González-Recio I, et al. Among authors: gil pitarch c. Nat Commun. 2022 Nov 25;13(1):6816. doi: 10.1038/s41467-022-34262-0. Nat Commun. 2022. PMID: 36433951 Free PMC article.
The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent.
Goikoetxea-Usandizaga N, Bravo M, Egia-Mendikute L, Abecia L, Serrano-Maciá M, Urdinguio RG, Clos-García M, Rodríguez-Agudo R, Araujo-Legido R, López-Bermudo L, Delgado TC, Lachiondo-Ortega S, González-Recio I, Gil-Pitarch C, Peña-Cearra A, Simón J, Benedé-Ubieto R, Ariño S, Herranz JM, Azkargorta M, Salazar-Bermeo J, Martí N, Varela-Rey M, Falcón-Pérez JM, Lorenzo Ó, Nogueiras R, Elortza F, Nevzorova YA, Cubero FJ, Saura D, Martínez-Cruz LA, Sabio G, Palazón A, Sancho-Bru P, Elguezabal N, Fraga MF, Ávila MA, Bataller R, Marín JJG, Martín F, Martínez-Chantar ML. Goikoetxea-Usandizaga N, et al. Among authors: gil pitarch c. Hepatology. 2023 Sep 1;78(3):878-895. doi: 10.1097/HEP.0000000000000303. Epub 2023 Feb 9. Hepatology. 2023. PMID: 36745935 Free PMC article.
Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1.
Rodríguez-Agudo R, González-Recio I, Serrano-Maciá M, Bravo M, Petrov P, Blaya D, Herranz JM, Mercado-Gómez M, Rejano-Gordillo CM, Lachiondo-Ortega S, Gil-Pitarch C, Azkargorta M, Van Liempd SM, Martinez-Cruz LA, Simão AL, Elortza F, Martín C, Nevzorova YA, Cubero FJ, Delgado TC, Argemi J, Bataller R, Schoonjans K, Banales JM, Castro RE, Sancho-Bru P, Avila MA, Julve J, Jover R, Mabe J, Simon J, Goikoetxea-Usandizaga N, Martínez-Chantar ML. Rodríguez-Agudo R, et al. Among authors: gil pitarch c. JHEP Rep. 2023 Sep 30;6(1):100918. doi: 10.1016/j.jhepr.2023.100918. eCollection 2024 Jan. JHEP Rep. 2023. PMID: 38192540 Free PMC article.
The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes.
Mercado-Gómez M, Prieto-Fernández E, Goikoetxea-Usandizaga N, Vila-Vecilla L, Azkargorta M, Bravo M, Serrano-Maciá M, Egia-Mendikute L, Rodríguez-Agudo R, Lachiondo-Ortega S, Lee SY, Eguileor Giné A, Gil-Pitarch C, González-Recio I, Simón J, Petrov P, Jover R, Martínez-Cruz LA, Ereño-Orbea J, Delgado TC, Elortza F, Jiménez-Barbero J, Nogueiras R, Prevot V, Palazon A, Martínez-Chantar ML. Mercado-Gómez M, et al. Among authors: gil pitarch c. Commun Biol. 2022 Aug 17;5(1):827. doi: 10.1038/s42003-022-03789-9. Commun Biol. 2022. PMID: 35978143 Free PMC article.
Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen.
Rodríguez-Agudo R, Goikoetxea-Usandizaga N, Serrano-Maciá M, Fernández-Tussy P, Fernández-Ramos D, Lachiondo-Ortega S, González-Recio I, Gil-Pitarch C, Mercado-Gómez M, Morán L, Bizkarguenaga M, Lopitz-Otsoa F, Petrov P, Bravo M, Van Liempd SM, Falcon-Perez JM, Zabala-Letona A, Carracedo A, Castell JV, Jover R, Martínez-Cruz LA, Delgado TC, Cubero FJ, Lucena MI, Andrade RJ, Mabe J, Simón J, Martínez-Chantar ML. Rodríguez-Agudo R, et al. Among authors: gil pitarch c. Antioxidants (Basel). 2022 Apr 30;11(5):897. doi: 10.3390/antiox11050897. Antioxidants (Basel). 2022. PMID: 35624761 Free PMC article.
Structural insight into the unique conformation of cystathionine β-synthase from Toxoplasma gondii.
Fernández-Rodríguez C, Oyenarte I, Conter C, González-Recio I, Núñez-Franco R, Gil-Pitarch C, Quintana I, Jiménez-Osés G, Dominici P, Martinez-Chantar ML, Astegno A, Martínez-Cruz LA. Fernández-Rodríguez C, et al. Among authors: gil pitarch c. Comput Struct Biotechnol J. 2021 Jun 6;19:3542-3555. doi: 10.1016/j.csbj.2021.05.052. eCollection 2021. Comput Struct Biotechnol J. 2021. PMID: 34194677 Free PMC article.