Comparative results of central corneal thickness measurements in primary open-angle glaucoma, pseudoexfoliation glaucoma, and ocular hypertension

Ophthalmic Surg Lasers Imaging. 2008 Jan-Feb;39(1):17-21. doi: 10.3928/15428877-20080101-05.

Abstract

Background and objective: As clinical measurements of corneal thickness have become widely available, several studies found a positive correlation between central corneal thickness and applanation tonometry measurements. This study evaluated central corneal thickness in different types of glaucoma.

Patients and methods: An observational cross-sectional study assessed central corneal thickness using a specular microscope in the following groups of patients: 60 eyes with primary open-angle glaucoma, 50 eyes with pseudoexfoliation glaucoma, 50 eyes with ocular hypertension, and 60 eyes without glaucoma or ocular hypertension (control group).

Results: Central corneal thickness was significantly thinner in cases with pseudoexfoliation glaucoma (P < .0001) and significantly thicker in cases with ocular hypertension (P< .0001).

Conclusions: These results agree with the literature, strengthening the position that central corneal thickness varies in different types of glaucoma and, therefore, is a parameter that should be taken under consideration, especially when evaluating cases of pseudoexfoliative glaucoma and ocular hypertension.

Publication types

  • Comparative Study

MeSH terms

  • Anthropometry
  • Body Weights and Measures
  • Cornea / pathology*
  • Cross-Sectional Studies
  • Exfoliation Syndrome / diagnosis*
  • Glaucoma, Open-Angle / diagnosis*
  • Humans
  • Intraocular Pressure
  • Middle Aged
  • Ocular Hypertension / diagnosis
  • Tonometry, Ocular