Bioactive Compounds and Their Effect on Blood Pressure-A Review

Nutrients. 2020 Jun 3;12(6):1659. doi: 10.3390/nu12061659.

Abstract

Elevated blood pressure affects a great part of the elderly population and is the leading risk factor for cardiovascular disease. New approaches have been taken in the fight against this growing problem, in the form of diets (Mediterranean, Dietary Approaches to Stop Hypertension (DASH) and intermittent fasting). Recent research has shown the promising results regarding diets and their effect on the prevention and improvement of elevated blood pressure. This review attempts to take this a step further, reviewing 26 studies in the search for dietary elements that may be causing this improvement. Although good evidence was found in favor of lycopene, Docosahexaenoic acid (DHA), fiber and anthocyanin, further evidence is needed before any conclusions can be made. In contrast, the evidence shows that licorice increases blood pressure.

Keywords: blood pressure; hypertension; nutrition; therapy.

Publication types

  • Systematic Review

MeSH terms

  • Anthocyanins / pharmacology*
  • Blood Pressure / drug effects*
  • Diet, Mediterranean*
  • Dietary Approaches To Stop Hypertension / methods*
  • Dietary Fiber*
  • Docosahexaenoic Acids / pharmacology*
  • Fasting / physiology*
  • Female
  • Glycyrrhiza / adverse effects
  • Heart Disease Risk Factors
  • Humans
  • Hypertension / prevention & control*
  • Lycopene / pharmacology*
  • Male

Substances

  • Anthocyanins
  • Dietary Fiber
  • Docosahexaenoic Acids
  • Lycopene