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Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions.
Xu G, Liu Z, Wang X, Lu T, DesJarlais RL, Thieu T, Zhang J, Devine ZH, Du F, Li Q, Milligan CM, Shaffer P, Cedervall PE, Spurlino JC, Stratton CF, Pietrak B, Szewczuk LM, Wong V, Steele RA, Bruinzeel W, Chintala M, Silva J, Gaul MD, Macielag MJ, Nargund R. Xu G, et al. Among authors: stratton cf. J Med Chem. 2022 Aug 11;65(15):10419-10440. doi: 10.1021/acs.jmedchem.2c00442. Epub 2022 Jul 21. J Med Chem. 2022. PMID: 35862732
Transition State Structure of RNA Depurination by Saporin L3.
Yuan H, Stratton CF, Schramm VL. Yuan H, et al. Among authors: stratton cf. ACS Chem Biol. 2016 May 20;11(5):1383-90. doi: 10.1021/acschembio.5b01069. Epub 2016 Mar 8. ACS Chem Biol. 2016. PMID: 26886255 Free PMC article.
17 results