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Allogeneic Hematopoietic Cell Transplantation Improves Outcome in Myelodysplastic Syndrome Across High-Risk Genetic Subgroups: Genetic Analysis of the Blood and Marrow Transplant Clinical Trials Network 1102 Study.
Versluis J, Saber W, Tsai HK, Gibson CJ, Dillon LW, Mishra A, McGuirk J, Maziarz RT, Westervelt P, Hegde P, Mukherjee D, Martens MJ, Logan B, Horowitz M, Hourigan CS, Nakamura R, Cutler C, Lindsley RC; Blood and Marrow Transplant Clinical Trials Network. Versluis J, et al. J Clin Oncol. 2023 Oct 1;41(28):4497-4510. doi: 10.1200/JCO.23.00866. Epub 2023 Aug 22. J Clin Oncol. 2023. PMID: 37607457 Free PMC article.
RESULTS: The distribution of gene mutations was similar in the donor and no donor arms, with TP53 (28% v 29%; P = .89), ASXL1 (23% v 29%; P = .37), and SRSF2 (16% v 16%; P = .99) being most common. OS in patients with a TP53 mutation was worse compared with p …
RESULTS: The distribution of gene mutations was similar in the donor and no donor arms, with TP53 (28% v 29%; P = .89), ASXL1 (23% v …
Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19.
Gupta N, Settle L, Brown BR, Armaignac DL, Baram M, Perkins NE, Kaufman M, Melamed RR, Christie AB, Danesh VC, Denson JL, Cheruku SR, Boman K, Bansal V, Kumar VK, Walkey AJ, Domecq JP, Kashyap R, Aston CE; Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group. Gupta N, et al. Crit Care Med. 2022 Oct 1;50(10):e744-e758. doi: 10.1097/CCM.0000000000005627. Epub 2022 Jul 27. Crit Care Med. 2022. PMID: 35894609 Free PMC article.

Compared with those taking other AHAs only, patients on RAASIs only were younger (mean age 63.3 vs 66.9 yr; p < 0.0001), more often male (58.2% vs 52.4%; p = 0.0001) and more often White (55.1% vs 47.2%; p < 0.0001). ...Patients on RAASIs only had lower

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Compared with those taking other AHAs only, patients on RAASIs only were younger (mean age 63.3 vs 66.9 yr; p < 0.0001), more ofte

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Early Albumin Exposure After Cardiac Surgery.
Thang C, Marella P, Kumar A, Matebele M, Ramanan M. Thang C, et al. J Cardiothorac Vasc Anesth. 2022 May;36(5):1310-1317. doi: 10.1053/j.jvca.2021.07.011. Epub 2021 Jul 10. J Cardiothorac Vasc Anesth. 2022. PMID: 34344597

Patients exposed to albumin during the first 24 hours of ICU admission had a statistically significant reduction in mortality (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.48-0.97, p < 0.05) after adjustment for age, the Oxford Acute Severity of Illness Score,

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Patients exposed to albumin during the first 24 hours of ICU admission had a statistically significant reduction in mortality (odds ratio [O …
Metabolic Syndrome and Acute Respiratory Distress Syndrome in Hospitalized Patients With COVID-19.
Denson JL, Gillet AS, Zu Y, Brown M, Pham T, Yoshida Y, Mauvais-Jarvis F, Douglas IS, Moore M, Tea K, Wetherbie A, Stevens R, Lefante J, Shaffer JG, Armaignac DL, Belden KA, Kaufman M, Heavner SF, Danesh VC, Cheruku SR, St Hill CA, Boman K, Deo N, Bansal V, Kumar VK, Walkey AJ, Kashyap R; Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group. Denson JL, et al. JAMA Netw Open. 2021 Dec 1;4(12):e2140568. doi: 10.1001/jamanetworkopen.2021.40568. JAMA Netw Open. 2021. PMID: 34935924 Free PMC article.
In adjusted analyses, metabolic syndrome was associated with increased risk of ICU admission (adjusted odds ratio [aOR], 1.32 [95% CI, 1.14-1.53]), invasive mechanical ventilation (aOR, 1.45 [95% CI, 1.28-1.65]), ARDS (aOR, 1.36 [95% CI, 1.12-1.66]), and mortality (aOR, 1.19 [95% …
In adjusted analyses, metabolic syndrome was associated with increased risk of ICU admission (adjusted odds ratio [aOR], 1.32 [95% CI, 1.14- …
Stress hyperglycaemia or diabetes mellitus in cervicofacial infections? A Maxillofacial Surgery Trainee Research Collaborative (MTReC) study.
MTReC Writing group; MTReC Collaborative. MTReC Writing group, et al. Br J Oral Maxillofac Surg. 2022 Oct;60(8):1049-1055. doi: 10.1016/j.bjoms.2021.01.020. Epub 2021 Mar 24. Br J Oral Maxillofac Surg. 2022. PMID: 36075793
Patients diagnosed with DM were more likely to have infections arising from a salivary source (13% vs 4%, p<0.00), more returns to theatre (9% vs 2%, p<0.00), and a longer hospital stay (median (range) 2 (0-34) vs 1 (0-139) day, p=0.01) than non-DM pati …
Patients diagnosed with DM were more likely to have infections arising from a salivary source (13% vs 4%, p<0.00), more returns to …
Multi-site evaluation of advanced practice hand therapy clinics for the management of patients with trigger digit.
Burton C, Palmer MA, Fanton L, Cox R, Wishart LR. Burton C, et al. J Hand Ther. 2022 Oct-Dec;35(4):655-664. doi: 10.1016/j.jht.2021.06.007. Epub 2021 Jul 29. J Hand Ther. 2022. PMID: 34334276
Michigan Hand Outcome Questionnaire scores showed greater improvement in those not requiring SOPD review (P< .001~25.9 vs 4.2). Regression analysis identified a negative association between initial total Michigan Hand Outcome Questionnaire scores and unfavorable dischar …
Michigan Hand Outcome Questionnaire scores showed greater improvement in those not requiring SOPD review (P< .001~25.9 vs 4.2). Re …
The genetic landscape of severe combined immunodeficiency in the United States and Canada in the current era (2010-2018).
Dvorak CC, Haddad E, Buckley RH, Cowan MJ, Logan B, Griffith LM, Kohn DB, Pai SY, Notarangelo L, Shearer W, Prockop S, Kapoor N, Heimall J, Chaudhury S, Shyr D, Chandra S, Cuvelier G, Moore T, Shenoy S, Goldman F, Smith AR, Sunkersett G, Vander Lugt M, Caywood E, Quigg T, Torgerson T, Chandrakasan S, Craddock J, Dávila Saldaña BJ, Gillio A, Shereck E, Aquino V, DeSantes K, Knutsen A, Thakar M, Yu L, Puck JM. Dvorak CC, et al. J Allergy Clin Immunol. 2019 Jan;143(1):405-407. doi: 10.1016/j.jaci.2018.08.027. Epub 2018 Sep 5. J Allergy Clin Immunol. 2019. PMID: 30193840 Free PMC article. Clinical Trial.
Predicting Peak Productivity in Urologic Medicare Practice via Work-Relative Value Units.
Briggs L, Labban M, Ye J, Herzog P, Jones AN, Nguyen DD, Wallis CJD, Wolter C, Porten S, Trinh QD. Briggs L, et al. Urology. 2024 Apr 20:S0090-4295(24)00283-8. doi: 10.1016/j.urology.2024.03.037. Online ahead of print. Urology. 2024. PMID: 38648950
Millennials produced 1115 wRVUs per year, while Gen X and Baby Boomers produced significantly more (1997 and 2104, respectively, p<.01). Post-War urologists produced numerically more (1287, p=.88). ...
Millennials produced 1115 wRVUs per year, while Gen X and Baby Boomers produced significantly more (1997 and 2104, respectively, p&lt …
Airway management, intensive care requirement, and corticosteroid use in cervicofacial infection. A Maxillofacial Trainee Research Collaborative (MTReC) study.
MTReC Writing Group; MTReC Collaborative. MTReC Writing Group, et al. Br J Oral Maxillofac Surg. 2022 Nov;60(9):1228-1233. doi: 10.1016/j.bjoms.2022.07.013. Epub 2022 Aug 27. Br J Oral Maxillofac Surg. 2022. PMID: 36155700
Those who received steroids were more likely to remain intubated postoperatively (p = 0.006), require a higher level of postoperative care (p &lt; 0.001), and require a return to theatre (p = 0.019). ...
Those who received steroids were more likely to remain intubated postoperatively (p = 0.006), require a higher level of postoperative …
21 results