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Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.
Loo L, Waller MA, Moreno CL, Cole AJ, Stella AO, Pop OT, Jochum AK, Ali OH, Denes CE, Hamoudi Z, Chung F, Aggarwal A, Low JKK, Patel K, Siddiquee R, Kang T, Mathivanan S, Mackay JP, Jochum W, Flatz L, Hesselson D, Turville S, Neely GG. Loo L, et al. Among authors: denes ce. PLoS Biol. 2023 Feb 9;21(2):e3001967. doi: 10.1371/journal.pbio.3001967. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36757924 Free PMC article.
CRISPR activation screens: navigating technologies and applications.
Clark T, Waller MA, Loo L, Moreno CL, Denes CE, Neely GG. Clark T, et al. Among authors: denes ce. Trends Biotechnol. 2024 Mar 15:S0167-7799(24)00036-2. doi: 10.1016/j.tibtech.2024.02.007. Online ahead of print. Trends Biotechnol. 2024. PMID: 38493051 Free article. Review.
The VEGAS Platform Is Unsuitable for Mammalian Directed Evolution.
Denes CE, Cole AJ, Tran MTN, Mohd Khalid MKN, Hewitt AW, Hesselson D, Neely GG. Denes CE, et al. ACS Synth Biol. 2022 Oct 21;11(10):3544-3549. doi: 10.1021/acssynbio.2c00460. Epub 2022 Oct 11. ACS Synth Biol. 2022. PMID: 36219697