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The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain.
Glia. 2020 Oct;68(10):2119-2135. doi: 10.1002/glia.23831. Epub 2020 Mar 27.
Glia. 2020.
PMID: 32220118
Potassium Channels Kv1.3 and Kir2.1 But Not Kv1.5 Contribute to BV2 Cell Line and Primary Microglial Migration.
Anton R, Ghenghea M, Ristoiu V, Gattlen C, Suter MR, Cojocaru PA, Popa-Wagner A, Catalin B, Deftu AF.
Anton R, et al. Among authors: gattlen c.
Int J Mol Sci. 2021 Feb 19;22(4):2081. doi: 10.3390/ijms22042081.
Int J Mol Sci. 2021.
PMID: 33669857
Free PMC article.
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Spinal Cord T-Cell Infiltration in the Rat Spared Nerve Injury Model: A Time Course Study.
Gattlen C, Clarke CB, Piller N, Kirschmann G, Pertin M, Decosterd I, Gosselin RD, Suter MR.
Gattlen C, et al.
Int J Mol Sci. 2016 Mar 9;17(3):352. doi: 10.3390/ijms17030352.
Int J Mol Sci. 2016.
PMID: 27005622
Free PMC article.
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