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Identification of novel drugs to target dormant micrometastases.
Hurst RE, Hauser PJ, You Y, Bailey-Downs LC, Bastian A, Matthews SM, Thorpe J, Earle C, Bourguignon LY, Ihnat MA. Hurst RE, et al. Among authors: earle c. BMC Cancer. 2015 May 14;15:404. doi: 10.1186/s12885-015-1409-4. BMC Cancer. 2015. PMID: 25971923 Free PMC article.
Interaction of low molecular weight hyaluronan with CD44 and toll-like receptors promotes the actin filament-associated protein 110-actin binding and MyD88-NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invasion.
Bourguignon LY, Wong G, Earle CA, Xia W. Bourguignon LY, et al. Among authors: earle ca. Cytoskeleton (Hoboken). 2011 Dec;68(12):671-93. doi: 10.1002/cm.20544. Epub 2011 Nov 29. Cytoskeleton (Hoboken). 2011. PMID: 22031535 Free PMC article.