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GMP-Compliant Manufacturing of TRUCKs: CAR T Cells targeting GD2 and Releasing Inducible IL-18.
Glienke W, Dragon AC, Zimmermann K, Martyniszyn-Eiben A, Mertens M, Abken H, Rossig C, Altvater B, Aleksandrova K, Arseniev L, Kloth C, Stamopoulou A, Moritz T, Lode HN, Siebert N, Blasczyk R, Goudeva L, Schambach A, Köhl U, Eiz-Vesper B, Esser R. Glienke W, et al. Among authors: kloth c. Front Immunol. 2022 Mar 24;13:839783. doi: 10.3389/fimmu.2022.839783. eCollection 2022. Front Immunol. 2022. PMID: 35401506 Free PMC article.
Rescue from Pseudomonas aeruginosa Airway Infection via Stem Cell Transplantation.
Brinkert K, Hedtfeld S, Burhop A, Gastmeier R, Gad P, Wedekind D, Kloth C, Rothschuh J, Lachmann N, Hetzel M, Jirmo AC, Lopez-Rodriguez E, Brandenberger C, Hansen G, Schambach A, Ackermann M, Tümmler B, Munder A. Brinkert K, et al. Among authors: kloth c. Mol Ther. 2021 Mar 3;29(3):1324-1334. doi: 10.1016/j.ymthe.2020.12.003. Epub 2020 Dec 3. Mol Ther. 2021. PMID: 33279724 Free PMC article.
Histamine regulates murine primary dendritic cell functions.
Schenk H, Neumann D, Kloth C. Schenk H, et al. Among authors: kloth c. Immunopharmacol Immunotoxicol. 2016 Oct;38(5):379-84. doi: 10.1080/08923973.2016.1214144. Epub 2016 Aug 10. Immunopharmacol Immunotoxicol. 2016. PMID: 27560832
cCMP causes caspase-dependent apoptosis in mouse lymphoma cell lines.
Wolter S, Kloth C, Golombek M, Dittmar F, Försterling L, Seifert R. Wolter S, et al. Among authors: kloth c. Biochem Pharmacol. 2015 Nov 1;98(1):119-31. doi: 10.1016/j.bcp.2015.08.096. Epub 2015 Aug 20. Biochem Pharmacol. 2015. PMID: 26300059
CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation.
Dragon AC, Zimmermann K, Nerreter T, Sandfort D, Lahrberg J, Klöß S, Kloth C, Mangare C, Bonifacius A, Tischer-Zimmermann S, Blasczyk R, Maecker-Kolhoff B, Uchanska-Ziegler B, Abken H, Schambach A, Hudecek M, Eiz-Vesper B. Dragon AC, et al. Among authors: kloth c. J Immunother Cancer. 2020 Oct;8(2):e000736. doi: 10.1136/jitc-2020-000736. J Immunother Cancer. 2020. PMID: 33127653 Free PMC article.
Design and Characterization of an "All-in-One" Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines.
Zimmermann K, Kuehle J, Dragon AC, Galla M, Kloth C, Rudek LS, Sandalcioglu IE, Neyazi B, Moritz T, Meyer J, Rossig C, Altvater B, Eiz-Vesper B, Morgan MA, Abken H, Schambach A. Zimmermann K, et al. Among authors: kloth c. Cancers (Basel). 2020 Feb 6;12(2):375. doi: 10.3390/cancers12020375. Cancers (Basel). 2020. PMID: 32041222 Free PMC article.
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