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Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target.
Lechner S, Malgapo MIP, Grätz C, Steimbach RR, Baron A, Rüther P, Nadal S, Stumpf C, Loos C, Ku X, Prokofeva P, Lautenbacher L, Heimburg T, Würf V, Meng C, Wilhelm M, Sippl W, Kleigrewe K, Pauling JK, Kramer K, Miller AK, Pfaffl MW, Linder ME, Kuster B, Médard G. Lechner S, et al. Among authors: gratz c. Nat Chem Biol. 2022 Aug;18(8):812-820. doi: 10.1038/s41589-022-01015-5. Epub 2022 Apr 28. Nat Chem Biol. 2022. PMID: 35484434 Free PMC article.
Non-invasive and high-throughput interrogation of exon-specific isoform expression.
Truong DJ, Phlairaharn T, Eßwein B, Gruber C, Tümen D, Baligács E, Armbrust N, Vaccaro FL, Lederer EM, Beck EM, Geilenkeuser J, Göppert S, Krumwiede L, Grätz C, Raffl G, Schwarz D, Zirngibl M, Živanić M, Beyer M, Körner JD, Santl T, Evsyukov V, Strauß T, Schwarz SC, Höglinger GU, Heutink P, Doll S, Conrad M, Giesert F, Wurst W, Westmeyer GG. Truong DJ, et al. Among authors: gratz c. Nat Cell Biol. 2021 Jun;23(6):652-663. doi: 10.1038/s41556-021-00678-x. Epub 2021 Jun 3. Nat Cell Biol. 2021. PMID: 34083785 Free PMC article.
Author Correction: Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target.
Lechner S, Malgapo MIP, Grätz C, Steimbach RR, Baron A, Rüther P, Nadal S, Stumpf C, Loos C, Ku X, Prokofeva P, Lautenbacher L, Heimburg T, Würf V, Meng C, Wilhelm M, Sippl W, Kleigrewe K, Pauling JK, Kramer K, Miller AK, Pfaffl MW, Linder ME, Kuster B, Médard G. Lechner S, et al. Among authors: gratz c. Nat Chem Biol. 2022 Aug;18(8):913. doi: 10.1038/s41589-022-01112-5. Nat Chem Biol. 2022. PMID: 35840679 No abstract available.
Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.
Schuster M, Braun FK, Chiang DM, Ludwig C, Meng C, Grätz C, Kirchner B, Proescholdt M, Hau P, Steinlein OK, Pfaffl MW, Riemenschneider MJ, Reithmair M. Schuster M, et al. Among authors: gratz c. Front Immunol. 2024 Apr 25;15:1388769. doi: 10.3389/fimmu.2024.1388769. eCollection 2024. Front Immunol. 2024. PMID: 38726003 Free PMC article.