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The miR-200c/141-ZEB2-TGFβ axis is aberrant in human T-cell prolymphocytic leukemia.
Erkeland SJ, Stavast CJ, Schilperoord-Vermeulen J, Dal Collo G, Van de Werken HJG, Leon LG, Van Hoven-Beijen A, Van Zuijen I, Mueller YM, Bindels EM, De Ridder D, Kappers-Klunne MC, Van Lom K, Van der Velden VHJ, Langerak AW. Erkeland SJ, et al. Among authors: stavast cj. Haematologica. 2022 Jan 1;107(1):143-153. doi: 10.3324/haematol.2020.263756. Haematologica. 2022. PMID: 33596640 Free PMC article.
The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis.
Stavast CJ, van Zuijen I, Karkoulia E, Özçelik A, van Hoven-Beijen A, Leon LG, Voerman JSA, Janssen GMC, van Veelen PA, Burocziova M, Brouwer RWW, van IJcken WFJ, Maas A, Bindels EM, van der Velden VHJ, Schliehe C, Katsikis PD, Alberich-Jorda M, Erkeland SJ. Stavast CJ, et al. Leukemia. 2022 Mar;36(3):687-700. doi: 10.1038/s41375-021-01461-5. Epub 2021 Nov 5. Leukemia. 2022. PMID: 34741119 Free PMC article.
miR-181a is a novel player in the STAT3-mediated survival network of TCRαβ+ CD8+ T large granular lymphocyte leukemia.
Assmann JLJC, Leon LG, Stavast CJ, van den Bogaerdt SE, Schilperoord-Vermeulen J, Sandberg Y, Bellido M, Erkeland SJ, Feith DJ, Loughran TP Jr, Langerak AW. Assmann JLJC, et al. Among authors: stavast cj. Leukemia. 2022 Apr;36(4):983-993. doi: 10.1038/s41375-021-01480-2. Epub 2021 Dec 6. Leukemia. 2022. PMID: 34873301 Free PMC article.