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Page 1
Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Chofor R, Sooriyaarachchi S, Risseeuw MD, Bergfors T, Pouyez J, Johny C, Haymond A, Everaert A, Dowd CS, Maes L, Coenye T, Alex A, Couch RD, Jones TA, Wouters J, Mowbray SL, Van Calenbergh S. Chofor R, et al. Among authors: johny c. J Med Chem. 2015 Apr 9;58(7):2988-3001. doi: 10.1021/jm5014264. Epub 2015 Mar 31. J Med Chem. 2015. PMID: 25781377 Free article.
Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase).
Haymond A, Johny C, Dowdy T, Schweibenz B, Villarroel K, Young R, Mantooth CJ, Patel T, Bases J, San Jose G, Jackson ER, Dowd CS, Couch RD. Haymond A, et al. Among authors: johny c. PLoS One. 2014 Aug 29;9(8):e106243. doi: 10.1371/journal.pone.0106243. eCollection 2014. PLoS One. 2014. PMID: 25171339 Free PMC article.
Structure-Activity Relationships of the MEPicides: N-Acyl and O-Linked Analogs of FR900098 as Inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis.
San Jose G, Jackson ER, Haymond A, Johny C, Edwards RL, Wang X, Brothers RC, Edelstein EK, Odom AR, Boshoff HI, Couch RD, Dowd CS. San Jose G, et al. Among authors: johny c. ACS Infect Dis. 2016 Dec 9;2(12):923-935. doi: 10.1021/acsinfecdis.6b00125. Epub 2016 Oct 12. ACS Infect Dis. 2016. PMID: 27676224 Free PMC article.