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Page 1
Showing results for channel wilson
Search for Chantel Wilson instead (2 results)
Ion Channel Screening.
McManus OB, Garcia ML, Weaver D, Bryant M, Titus S, Herrington JB. McManus OB, et al. 2012 Oct 1. In: Markossian S, Grossman A, Brimacombe K, Arkin M, Auld D, Austin C, Baell J, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Wang Y, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. 2012 Oct 1. In: Markossian S, Grossman A, Brimacombe K, Arkin M, Auld D, Austin C, Baell J, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Wang Y, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. PMID: 23035274 Free Books & Documents. Review.
As such, ion channels are common targets for toxins and therapeutics. Ion channel screening assays have traditionally utilized indirect or low throughput approaches. ...Ion channels subtypes can display a variety of functional differences in gating and permea …
As such, ion channels are common targets for toxins and therapeutics. Ion channel screening assays have traditionally utilized …
Automated Electrophysiology Assays.
Priest BT, Cerne R, Krambis MJ, Schmalhofer WA, Wakulchik M, Wilenkin B, Burris KD. Priest BT, et al. 2017 Mar 9. In: Markossian S, Grossman A, Brimacombe K, Arkin M, Auld D, Austin C, Baell J, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Wang Y, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. 2017 Mar 9. In: Markossian S, Grossman A, Brimacombe K, Arkin M, Auld D, Austin C, Baell J, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Kales SC, Lal-Nag M, Li Z, McGee J, McManus O, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Wang Y, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. PMID: 28277626 Free Books & Documents. Review.
High-throughput, non-electrophysiology based primary assays were used successfully but lack key information content, such as voltage dependence and kinetics, and may not be suitable for all ion channels. Most importantly, non-electrophysiological assays lack the ability to …
High-throughput, non-electrophysiology based primary assays were used successfully but lack key information content, such as voltage depende …
Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, Lewin GR, Patapoutian A. Ranade SS, et al. Nature. 2014 Dec 4;516(7529):121-5. doi: 10.1038/nature13980. Nature. 2014. PMID: 25471886 Free PMC article.
Piezo2 is a rapidly adapting, mechanically activated ion channel expressed in a subset of sensory neurons of the dorsal root ganglion and in cutaneous mechanoreceptors known as Merkel-cell-neurite complexes. ...Notably, we find that touch and pain sensation are separable, …
Piezo2 is a rapidly adapting, mechanically activated ion channel expressed in a subset of sensory neurons of the dorsal root ganglion …
Two-Channel Charge-Kondo Physics in Graphene Quantum Dots.
Minarelli EL, Rigo JB, Mitchell AK. Minarelli EL, et al. Nanomaterials (Basel). 2022 Apr 29;12(9):1513. doi: 10.3390/nano12091513. Nanomaterials (Basel). 2022. PMID: 35564221 Free PMC article.
The model is solved using Wilson's Numerical Renormalization Group method, uncovering a rich phase diagram as a function of dot-lead coupling strength, channel asymmetry, and potential scattering. ...The strong coupling pseudogap Kondo phase is found to persi …
The model is solved using Wilson's Numerical Renormalization Group method, uncovering a rich phase diagram as a function of do …
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function.
Lyon M, Li P, Ferreira JJ, Lazarenko RM, Kharade SV, Kramer M, McClenahan SJ, Days E, Bauer JA, Spitznagel BD, Weaver CD, Borrego Alvarez A, Puga Molina LC, Lybaert P, Khambekar S, Liu A, Lindsley CW, Denton J, Santi CM. Lyon M, et al. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2212338120. doi: 10.1073/pnas.2212338120. Epub 2023 Jan 17. Proc Natl Acad Sci U S A. 2023. PMID: 36649421 Free PMC article.
In mouse sperm, hyperpolarization is caused by activation of the sperm-specific potassium (K(+)) channel SLO3 [C. M. Santi et al., FEBS Lett. 584, 1041-1046 (2010)]. In human sperm, it has long been unclear whether hyperpolarization depends on SLO3 or the ubiquitous K(+) …
In mouse sperm, hyperpolarization is caused by activation of the sperm-specific potassium (K(+)) channel SLO3 [C. M. Santi et al., FE …
The molecular makeup of peripheral and central baroreceptors: stretching a role for Transient Receptor Potential (TRP), Epithelial Sodium Channel (ENaC), Acid Sensing Ion Channel (ASIC), and Piezo channels.
Yang H, Tenorio Lopes L, Barioni NO, Roeske J, Incognito AV, Baker J, Raj SR, Wilson RJA. Yang H, et al. Cardiovasc Res. 2022 Dec 9;118(15):3052-3070. doi: 10.1093/cvr/cvab334. Cardiovasc Res. 2022. PMID: 34734981 Review.
Therefore, the purpose of this review is to (i) provide a brief overview of arterial and central baroreflex control of BP, (ii) review classes of ion channels currently proposed as the baroreflex mechanosensor, namely Transient Receptor Potential (TRP), Epithelial Sodium …
Therefore, the purpose of this review is to (i) provide a brief overview of arterial and central baroreflex control of BP, (ii) review class …
Polycystic kidney disease.
Wilson PD. Wilson PD. N Engl J Med. 2004 Jan 8;350(2):151-64. doi: 10.1056/NEJMra022161. N Engl J Med. 2004. PMID: 14711914 Review. No abstract available.
Structure and Computational Electrophysiology of Ac-LS3, a Synthetic Ion Channel.
Wilson MA, Pohorille A. Wilson MA, et al. J Phys Chem B. 2022 Nov 10;126(44):8985-8999. doi: 10.1021/acs.jpcb.2c05965. Epub 2022 Oct 28. J Phys Chem B. 2022. PMID: 36306164
Computer simulations are reported on Ac-LS3, a synthetic ion channel, containing 21 residues with a Leu-Ser-Ser-Leu-Leu-Ser-Leu heptad repeat, which forms ions channels upon application of voltage. ...The consistency between different methods is very good, supportin …
Computer simulations are reported on Ac-LS3, a synthetic ion channel, containing 21 residues with a Leu-Ser-Ser-Leu-Leu-Ser-Leu hepta …
Sodium channel activation underlies transfluthrin repellency in Aedes aegypti.
Andreazza F, Valbon WR, Wang Q, Liu F, Xu P, Bandason E, Chen M, Wu S, Smith LB, Scott JG, Jiang Y, Jiang D, Zhang A, Oliveira EE, Dong K. Andreazza F, et al. PLoS Negl Trop Dis. 2021 Jul 8;15(7):e0009546. doi: 10.1371/journal.pntd.0009546. eCollection 2021 Jul. PLoS Negl Trop Dis. 2021. PMID: 34237076 Free PMC article.
The 1S-cis isomer of transfluthrin, which does not activate sodium channels, does not elicit repellency. Mutations in the sodium channel gene that reduce the potency of transfluthrin on sodium channels decrease transfluthrin repellency but do not affect repel …
The 1S-cis isomer of transfluthrin, which does not activate sodium channels, does not elicit repellency. Mutations in the sodium c
1,919 results