High-glucose concentrations change DNA methylation levels in human IVM oocytes.
Wang Q, Tang SB, Song XB, Deng TF, Zhang TT, Yin S, Luo SM, Shen W, Zhang CL, Ge ZJ.
Wang Q, et al.
Hum Reprod. 2018 Mar 1;33(3):474-481. doi: 10.1093/humrep/dey006.
Hum Reprod. 2018.
PMID: 29377995
MI oocytes were cultured in medium with different glucose concentrations (control, 10 mM and 15 mM) in vitro and 48 h later, oocytes with first polar body extrusion were collected to check the DNA methylation levels. PARTICIPANTS/MATERIALS, SETTING, METHODS: MI oocy …
MI oocytes were cultured in medium with different glucose concentrations (control, 10 mM and 15 mM) in vitro and 48 h later, oocytes …