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Year Number of Results
2003 1
2005 1
2011 2
2012 4
2013 1
2017 1
2018 1
2022 1
2024 0

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12 results

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Page 1
Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials.
Amporndanai K, Pinthong N, O'Neill PM, Hong WD, Amewu RK, Pidathala C, Berry NG, Leung SC, Ward SA, Biagini GA, Hasnain SS, Antonyuk SV. Amporndanai K, et al. Among authors: pidathala c. Biology (Basel). 2022 Jul 25;11(8):1109. doi: 10.3390/biology11081109. Biology (Basel). 2022. PMID: 35892964 Free PMC article.
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
O'Neill PM, Amewu RK, Charman SA, Sabbani S, Gnädig NF, Straimer J, Fidock DA, Shore ER, Roberts NL, Wong MH, Hong WD, Pidathala C, Riley C, Murphy B, Aljayyoussi G, Gamo FJ, Sanz L, Rodrigues J, Cortes CG, Herreros E, Angulo-Barturén I, Jiménez-Díaz MB, Bazaga SF, Martínez-Martínez MS, Campo B, Sharma R, Ryan E, Shackleford DM, Campbell S, Smith DA, Wirjanata G, Noviyanti R, Price RN, Marfurt J, Palmer MJ, Copple IM, Mercer AE, Ruecker A, Delves MJ, Sinden RE, Siegl P, Davies J, Rochford R, Kocken CHM, Zeeman AM, Nixon GL, Biagini GA, Ward SA. O'Neill PM, et al. Among authors: pidathala c. Nat Commun. 2017 May 24;8:15159. doi: 10.1038/ncomms15159. Nat Commun. 2017. PMID: 28537265 Free PMC article.
Direct catalytic asymmetric enolexo aldolizations.
Pidathala C, Hoang L, Vignola N, List B. Pidathala C, et al. Angew Chem Int Ed Engl. 2003 Jun 23;42(24):2785-8. doi: 10.1002/anie.200351266. Angew Chem Int Ed Engl. 2003. PMID: 12820268 No abstract available.
Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication.
Stachulski AV, Pidathala C, Row EC, Sharma R, Berry NG, Iqbal M, Bentley J, Allman SA, Edwards G, Helm A, Hellier J, Korba BE, Semple JE, Rossignol JF. Stachulski AV, et al. Among authors: pidathala c. J Med Chem. 2011 Jun 23;54(12):4119-32. doi: 10.1021/jm200153p. Epub 2011 May 23. J Med Chem. 2011. PMID: 21553812 Free PMC article.
Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication.
Stachulski AV, Pidathala C, Row EC, Sharma R, Berry NG, Lawrenson AS, Moores SL, Iqbal M, Bentley J, Allman SA, Edwards G, Helm A, Hellier J, Korba BE, Semple JE, Rossignol JF. Stachulski AV, et al. Among authors: pidathala c. J Med Chem. 2011 Dec 22;54(24):8670-80. doi: 10.1021/jm201264t. Epub 2011 Nov 21. J Med Chem. 2011. PMID: 22059983
Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
Leung SC, Gibbons P, Amewu R, Nixon GL, Pidathala C, Hong WD, Pacorel B, Berry NG, Sharma R, Stocks PA, Srivastava A, Shone AE, Charoensutthivarakul S, Taylor L, Berger O, Mbekeani A, Hill A, Fisher NE, Warman AJ, Biagini GA, Ward SA, O'Neill PM. Leung SC, et al. Among authors: pidathala c. J Med Chem. 2012 Mar 8;55(5):1844-57. doi: 10.1021/jm201184h. Epub 2012 Feb 24. J Med Chem. 2012. PMID: 22364417 Free PMC article.
Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.
Sharma R, Lawrenson AS, Fisher NE, Warman AJ, Shone AE, Hill A, Mbekeani A, Pidathala C, Amewu RK, Leung S, Gibbons P, Hong DW, Stocks P, Nixon GL, Chadwick J, Shearer J, Gowers I, Cronk D, Parel SP, O'Neill PM, Ward SA, Biagini GA, Berry NG. Sharma R, et al. Among authors: pidathala c. J Med Chem. 2012 Apr 12;55(7):3144-54. doi: 10.1021/jm3001482. Epub 2012 Mar 22. J Med Chem. 2012. PMID: 22380711 Free PMC article.
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Biagini GA, Fisher N, Shone AE, Mubaraki MA, Srivastava A, Hill A, Antoine T, Warman AJ, Davies J, Pidathala C, Amewu RK, Leung SC, Sharma R, Gibbons P, Hong DW, Pacorel B, Lawrenson AS, Charoensutthivarakul S, Taylor L, Berger O, Mbekeani A, Stocks PA, Nixon GL, Chadwick J, Hemingway J, Delves MJ, Sinden RE, Zeeman AM, Kocken CH, Berry NG, O'Neill PM, Ward SA. Biagini GA, et al. Among authors: pidathala c. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8298-303. doi: 10.1073/pnas.1205651109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566611 Free PMC article.
In vitro efficacies of nitazoxanide and other thiazolides against Neospora caninum tachyzoites reveal antiparasitic activity independent of the nitro group.
Esposito M, Stettler R, Moores SL, Pidathala C, Müller N, Stachulski A, Berry NG, Rossignol JF, Hemphill A. Esposito M, et al. Among authors: pidathala c. Antimicrob Agents Chemother. 2005 Sep;49(9):3715-23. doi: 10.1128/AAC.49.9.3715-3723.2005. Antimicrob Agents Chemother. 2005. PMID: 16127045 Free PMC article.
12 results