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Coumarins effectively inhibit bacterial α-carbonic anhydrases.
Giovannuzzi S, Hewitt CS, Nocentini A, Capasso C, Flaherty DP, Supuran CT. Giovannuzzi S, et al. Among authors: hewitt cs. J Enzyme Inhib Med Chem. 2022 Dec;37(1):333-338. doi: 10.1080/14756366.2021.2012174. J Enzyme Inhib Med Chem. 2022. PMID: 34979838 Free PMC article.
Inhibition studies of bacterial α-carbonic anhydrases with phenols.
Giovannuzzi S, Hewitt CS, Nocentini A, Capasso C, Costantino G, Flaherty DP, Supuran CT. Giovannuzzi S, et al. Among authors: hewitt cs. J Enzyme Inhib Med Chem. 2022 Dec;37(1):666-671. doi: 10.1080/14756366.2022.2038592. J Enzyme Inhib Med Chem. 2022. PMID: 35139743 Free PMC article.
Structure-Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae.
Hewitt CS, Abutaleb NS, Elhassanny AEM, Nocentini A, Cao X, Amos DP, Youse MS, Holly KJ, Marapaka AK, An W, Kaur J, Krabill AD, Elkashif A, Elgammal Y, Graboski AL, Supuran CT, Seleem MN, Flaherty DP. Hewitt CS, et al. ACS Infect Dis. 2021 Jul 9;7(7):1969-1984. doi: 10.1021/acsinfecdis.1c00055. Epub 2021 Mar 25. ACS Infect Dis. 2021. PMID: 33765392 Free PMC article.
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