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Page 1
Pharmacotherapy, alternative and adjunctive therapies for eating disorders: findings from a rapid review.
Rodan SC, Bryant E, Le A, Maloney D, Touyz S, McGregor IS, Maguire S; National Eating Disorder Research Consortium. Rodan SC, et al. J Eat Disord. 2023 Jul 6;11(1):112. doi: 10.1186/s40337-023-00833-9. J Eat Disord. 2023. PMID: 37415200 Free PMC article. Review.
Some of the identified studies involved combinations of the above (e.g. adjunctive pharmacotherapy). Evidence of efficacy of interventions across all three categories was very limited with few relevant high quality clinical trials. ...
Some of the identified studies involved combinations of the above (e.g. adjunctive pharmacotherapy). Evidence of efficacy of interven …
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19.
ISARIC Clinical Characterization Group; Garcia-Gallo E, Merson L, Kennon K, Kelly S, Citarella BW, Fryer DV, Shrapnel S, Lee J, Duque S, Fuentes YV, Balan V, Smith S, Wei J, Gonçalves BP, Russell CD, Sigfrid L, Dagens A, Olliaro PL, Baruch J, Kartsonaki C, Dunning J, Rojek A, Rashan A, Beane A, Murthy S, Reyes LF. ISARIC Clinical Characterization Group, et al. Sci Data. 2022 Jul 30;9(1):454. doi: 10.1038/s41597-022-01534-9. Sci Data. 2022. PMID: 35908040 Free PMC article.
Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine.
Assouline S, Gasiorek J, Bergeron J, Lambert C, Culjkovic-Kraljacic B, Cocolakis E, Zakaria C, Szlachtycz D, Yee K, Borden KLB. Assouline S, et al. Haematologica. 2023 Nov 1;108(11):2946-2958. doi: 10.3324/haematol.2023.282791. Haematologica. 2023. PMID: 36951168 Free PMC article. Clinical Trial.
Glucuronidation is a common mechanism of drug inactivation impacting many AML therapies, e.g., cytarabine, decitabine, azacytidine and venetoclax. In AML cells, the capacity for glucuronidation arises from increased production of the UDP-glucuronosyltransferase 1A (UGT1A) …
Glucuronidation is a common mechanism of drug inactivation impacting many AML therapies, e.g., cytarabine, decitabine, azacytidine an …
The use of the Godin-Shephard Leisure-Time Physical Activity Questionnaire in oncology research: a systematic review.
Amireault S, Godin G, Lacombe J, Sabiston CM. Amireault S, et al. BMC Med Res Methodol. 2015 Aug 12;15:60. doi: 10.1186/s12874-015-0045-7. BMC Med Res Methodol. 2015. PMID: 26264621 Free PMC article. Review.
This study aimed to (i) document the frequency of use of the questionnaire for ranking (i.e., level of activity) and classification (i.e., active versus insufficiently active) purposes, (ii) summarize how the GSLTPAQ is used in terms of item content and scoring, and …
This study aimed to (i) document the frequency of use of the questionnaire for ranking (i.e., level of activity) and classification ( …
Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study.
Reyes LF, Murthy S, Garcia-Gallo E, Merson L, Ibáñez-Prada ED, Rello J, Fuentes YV, Martin-Loeches I, Bozza F, Duque S, Taccone FS, Fowler RA, Kartsonaki C, Gonçalves BP, Citarella BW, Aryal D, Burhan E, Cummings MJ, Delmas C, Diaz R, Figueiredo-Mello C, Hashmi M, Panda PK, Jiménez MP, Rincon DFB, Thomson D, Nichol A, Marshall JC, Olliaro PL; ISARIC Characterization Group. Reyes LF, et al. Crit Care. 2022 Sep 13;26(1):276. doi: 10.1186/s13054-022-04155-1. Crit Care. 2022. PMID: 36100904 Free PMC article.
In contrast, patients admitted in lower- and middle-income countries (LMICs) were less frequently treated with HFNC (16.1%) and the majority received IMV (59.1%). The failure rate of non-invasive respiratory support (i.e. HFNC or NIV) was 15.5%, of which 71.2% were from HI …
In contrast, patients admitted in lower- and middle-income countries (LMICs) were less frequently treated with HFNC (16.1%) and the majority …
Cetuximab combined with paclitaxel or paclitaxel alone for patients with recurrent or metastatic head and neck squamous cell carcinoma progressing after EXTREME.
Chevalier T, Daste A, Saada-Bouzid E, Loundou A, Peyraud F, Lambert T, Le Tourneau C, Peyrade F, Dupuis C, Alfonsi M, Fayette J, Reure J, Huguet F, Fakhry N, Toullec C, Salas S. Chevalier T, et al. Cancer Med. 2021 Jun;10(12):3952-3963. doi: 10.1002/cam4.3953. Epub 2021 May 25. Cancer Med. 2021. PMID: 34080776 Free PMC article.
Association between IgM anti-herpes simplex virus and plasma amyloid-beta levels.
Féart C, Helmer C, Fleury H, Béjot Y, Ritchie K, Amouyel P, Schraen-Maschke S, Buée L, Lambert JC, Letenneur L, Dartigues JF. Féart C, et al. PLoS One. 2011;6(12):e29480. doi: 10.1371/journal.pone.0029480. Epub 2011 Dec 28. PLoS One. 2011. PMID: 22216291 Free PMC article.
RESULTS: After adjustment for study center, age, sex, education, and apolipoprotein E-e4 polymorphism, plasma Abeta(1-42) and Abeta(1-40) levels were specifically inversely associated with anti-HSV IgM levels (beta = -20.7, P=0.001 and beta = -92.4, P=0.007, respectively). …
RESULTS: After adjustment for study center, age, sex, education, and apolipoprotein E-e4 polymorphism, plasma Abeta(1-42) and Abeta(1 …
Complementary use of mass spectrometry and cryo-electron microscopy to assess the maturity of live attenuated dengue vaccine viruses.
Trauchessec M, Lambert O, Bonnafous P, Berard Y, Barriere F, Huillet C, Marco S, Sirohi D, Hedrick V, Kuhn R, Guy B, Ronzon F, Manin C. Trauchessec M, et al. Vaccine. 2019 Jun 12;37(27):3580-3587. doi: 10.1016/j.vaccine.2019.05.012. Epub 2019 May 20. Vaccine. 2019. PMID: 31122859
The vaccine is composed of four recombinant, live, attenuated vaccines (CYD 1-4) based on a yellow fever vaccine 17D (YFV 17D) backbone, each expressing the pre-membrane (prM) and envelope (E) genes of one of the four DENV serotypes. Virus maturity could impact the biologi …
The vaccine is composed of four recombinant, live, attenuated vaccines (CYD 1-4) based on a yellow fever vaccine 17D (YFV 17D) backbone, eac …
The Scleroderma Patient-centered Intervention Network Self-Management (SPIN-SELF) Program: protocol for a two-arm parallel partially nested randomized controlled feasibility trial with progression to full-scale trial.
Nordlund J, Henry RS, Kwakkenbos L, Carrier ME, Levis B, Nielson WR, Bartlett SJ, Dyas L, Tao L, Fedoruk C, Nielsen K, Hudson M, Pope J, Frech T, Gholizadeh S, Johnson SR, Piotrowski P, Jewett LR, Gordon J, Chung L, Bilsker D, Levis AW, Turner KA, Cumin J, Welling J, Fortuné C, Leite C, Gottesman K, Sauve M, Rodríguez-Reyna TS, Larche M, van Breda W, Suarez-Almazor ME, Wurz A, Culos-Reed N, Malcarne VL, Mayes MD, Boutron I, Mouthon L, Benedetti A, Thombs BD; SPIN Investigators. Nordlund J, et al. Trials. 2021 Nov 27;22(1):856. doi: 10.1186/s13063-021-05827-z. Trials. 2021. PMID: 34838105 Free PMC article.
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