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Page 1
Novel synthetic pharmacophores inducing a stabilization of cellular microtubules.
Martinez A, Soleilhac E, Barette C, Prudent R, Gozzi GJ, Vassal-Stermann E, Pillet C, Di Pietro A, Fauvarque MO, Lafanechere L. Martinez A, et al. Among authors: pillet c. Curr Cancer Drug Targets. 2015;15(1):2-13. doi: 10.2174/1568009615666141215154149. Curr Cancer Drug Targets. 2015. PMID: 25543663
Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket.
Bancet A, Frem R, Jeanneret F, Mularoni A, Bazelle P, Roelants C, Delcros JG, Guichou JF, Pillet C, Coste I, Renno T, Battail C, Cochet C, Lomberget T, Filhol O, Krimm I. Bancet A, et al. Among authors: pillet c. iScience. 2024 Jan 12;27(2):108903. doi: 10.1016/j.isci.2024.108903. eCollection 2024 Feb 16. iScience. 2024. PMID: 38318383 Free PMC article.
Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction.
Giacosa S, Pillet C, Séraudie I, Guyon L, Wallez Y, Roelants C, Battail C, Evrard B, Chalmel F, Barette C, Soleilhac E, Fauvarque MO, Franquet Q, Sarrazin C, Peilleron N, Fiard G, Long JA, Descotes JL, Cochet C, Filhol O. Giacosa S, et al. Among authors: pillet c. Cancers (Basel). 2021 Feb 2;13(3):576. doi: 10.3390/cancers13030576. Cancers (Basel). 2021. PMID: 33540838 Free PMC article.
Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth.
Prudent R, Vassal-Stermann E, Nguyen CH, Pillet C, Martinez A, Prunier C, Barette C, Soleilhac E, Filhol O, Beghin A, Valdameri G, Honoré S, Aci-Sèche S, Grierson D, Antonipillai J, Li R, Di Pietro A, Dumontet C, Braguer D, Florent JC, Knapp S, Bernard O, Lafanechère L. Prudent R, et al. Among authors: pillet c. Cancer Res. 2012 Sep 1;72(17):4429-39. doi: 10.1158/0008-5472.CAN-11-3342. Epub 2012 Jul 3. Cancer Res. 2012. PMID: 22761334 Free article.
Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.
Prudent R, Vassal-Stermann É, Nguyen CH, Mollaret M, Viallet J, Desroches-Castan A, Martinez A, Barette C, Pillet C, Valdameri G, Soleilhac E, Di Pietro A, Feige JJ, Billaud M, Florent JC, Lafanechère L. Prudent R, et al. Among authors: pillet c. Br J Pharmacol. 2013 Feb;168(3):673-85. doi: 10.1111/j.1476-5381.2012.02230.x. Br J Pharmacol. 2013. PMID: 23004938 Free PMC article.