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A Strategy Utilizing Protein-Protein Interaction Hubs for the Treatment of Cancer Diseases.
Carels N, Sgariglia D, Junior MGV, Lima CR, Carneiro FRG, Silva GFD, Silva FABD, Scardini R, Tuszynski JA, Andrade CV, Monteiro AC, Martins MG, Silva TGD, Ferraz H, Finotelli PV, Balbino TA, Pinto JC. Carels N, et al. Among authors: lima cr. Int J Mol Sci. 2023 Nov 8;24(22):16098. doi: 10.3390/ijms242216098. Int J Mol Sci. 2023. PMID: 38003288 Free PMC article. Review.
Agathisflavone, a natural biflavonoid that inhibits SARS-CoV-2 replication by targeting its proteases.
Chaves OA, Lima CR, Fintelman-Rodrigues N, Sacramento CQ, de Freitas CS, Vazquez L, Temerozo JR, Rocha MEN, Dias SSG, Carels N, Bozza PT, Castro-Faria-Neto HC, Souza TML. Chaves OA, et al. Among authors: lima cr. Int J Biol Macromol. 2022 Dec 1;222(Pt A):1015-1026. doi: 10.1016/j.ijbiomac.2022.09.204. Epub 2022 Sep 29. Int J Biol Macromol. 2022. PMID: 36183752 Free PMC article.
Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production.
Fintelman-Rodrigues N, Sacramento CQ, Ribeiro Lima C, Souza da Silva F, Ferreira AC, Mattos M, de Freitas CS, Cardoso Soares V, da Silva Gomes Dias S, Temerozo JR, Miranda MD, Matos AR, Bozza FA, Carels N, Alves CR, Siqueira MM, Bozza PT, Souza TML. Fintelman-Rodrigues N, et al. Among authors: ribeiro lima c. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00825-20. doi: 10.1128/AAC.00825-20. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32759267 Free PMC article.
A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major.
Catharina L, Lima CR, Franca A, Guimarães ACR, Alves-Ferreira M, Tuffery P, Derreumaux P, Carels N. Catharina L, et al. Among authors: lima cr. Bioinform Biol Insights. 2017 Jun 12;11:1177932217712471. doi: 10.1177/1177932217712471. eCollection 2017. Bioinform Biol Insights. 2017. PMID: 28638238 Free PMC article.