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Role of factor XIII in ischemic stroke: a key molecule promoting thrombus stabilization and resistance to lysis.
Marta-Enguita J, Navarro-Oviedo M, Machado FJDM, Bermejo R, Aymerich N, Herrera M, Zandio B, Pagola J, Juega J, Marta-Moreno J, Rodriguez JA, Páramo JA, Roncal C, Muñoz R, Orbe J. Marta-Enguita J, et al. J Thromb Haemost. 2024 Apr;22(4):1080-1093. doi: 10.1016/j.jtha.2023.12.029. Epub 2023 Dec 30. J Thromb Haemost. 2024. PMID: 38160727 Free article.
OBJECTIVES: To evaluate the effect of FXIII inhibition in a mouse model of ischemic stroke (IS) and the role of activated FXIII (FXIIIa) in clot formation and lysis in patients with IS. METHODS: A ferric chloride IS murine model was performed before and after administratio …
OBJECTIVES: To evaluate the effect of FXIII inhibition in a mouse model of ischemic stroke (IS) and the role of activated FXIII (FXIIIa) in …
Unveiling microbial preservation under hyperacidic and oxidizing conditions in the Oligocene Rio Tinto deposit.
Fernández-Remolar DC, Carrizo D, Harir M, Huang T, Amils R, Schmitt-Kopplin P, Sánchez-García L, Gomez-Ortiz D, Malmberg P. Fernández-Remolar DC, et al. Sci Rep. 2021 Nov 2;11(1):21543. doi: 10.1038/s41598-021-00730-8. Sci Rep. 2021. PMID: 34728655 Free PMC article.
In this paper, an exhaustive mass spectrometry investigation of ferric subsurface materials in the Rio Tinto gossan deposit (~ 25 Ma) provides evidence of well-preserved molecular biosignatures under oxidative and acidic conditions. ...
In this paper, an exhaustive mass spectrometry investigation of ferric subsurface materials in the Rio Tinto gossan deposit (~ 25 Ma) …
Intravenous Iron Replacement Improves Exercise Tolerance in COPD: A Single-Blind Randomized Trial.
Martín-Ontiyuelo C, Rodó-Pin A, Echeverría-Esnal D, Admetlló M, Duran-Jordà X, Alvarado M, Gea J, Barreiro E, Rodríguez-Chiaradía DA. Martín-Ontiyuelo C, et al. Arch Bronconeumol. 2022 Oct;58(10):689-698. doi: 10.1016/j.arbres.2021.08.011. Epub 2021 Sep 3. Arch Bronconeumol. 2022. PMID: 35312562 Clinical Trial. English, Spanish.
Patients were randomized at a 2:1 ratio to receive intravenous ferric carboxymaltose or placebo. The primary objective was to investigate whether intravenous iron replacement improved endurance time from baseline by at least 33%. ...RESULTS: We included 66 patients, 44 (66 …
Patients were randomized at a 2:1 ratio to receive intravenous ferric carboxymaltose or placebo. The primary objective was to investi …
Curauá-derived carbon dots: Fluorescent probes for effective Fe(III) ion detection, cellular labeling and bioimaging.
Raja S, Buhl EM, Dreschers S, Schalla C, Zenke M, Sechi A, Mattoso LHC. Raja S, et al. Mater Sci Eng C Mater Biol Appl. 2021 Oct;129:112409. doi: 10.1016/j.msec.2021.112409. Epub 2021 Sep 2. Mater Sci Eng C Mater Biol Appl. 2021. PMID: 34579918
C-dots were highly selective and effective for the detection of ferric Fe(III) ion in an aqueous medium with a detection limit of 0.77 muM in the linear range of 0-30 muM, a value much lower than the guideline limits proposed by the World Health Organization (WHO). ...
C-dots were highly selective and effective for the detection of ferric Fe(III) ion in an aqueous medium with a detection limit of 0.7 …
Dietary total antioxidant capacity and mortality in the PREDIMED study.
Henríquez-Sánchez P, Sánchez-Villegas A, Ruano-Rodríguez C, Gea A, Lamuela-Raventós RM, Estruch R, Salas-Salvadó J, Covas MI, Corella D, Schröder H, Gutiérrez-Bedmar M, Santos-Lozano JM, Pintó X, Arós F, Fiol M, Tresserra-Rimbau A, Ros E, Martínez-González MA, Serra-Majem L. Henríquez-Sánchez P, et al. Eur J Nutr. 2016 Feb;55(1):227-36. doi: 10.1007/s00394-015-0840-2. Epub 2015 Feb 7. Eur J Nutr. 2016. PMID: 25663609 Free article. Clinical Trial.
Cox regression models were fitted to assess the relationship between dietary total antioxidant capacity and mortality. Dietary total antioxidant capacity was estimated using ferric-reducing antioxidant power assays. RESULTS: A total of 319 deaths were recorded after a medi …
Cox regression models were fitted to assess the relationship between dietary total antioxidant capacity and mortality. Dietary total antioxi …
Antioxidant and Antibacterial Properties of Carbosilane Dendrimers Functionalized with Polyphenolic Moieties.
Sanz Del Olmo N, Peña González CE, Rojas JD, Gómez R, Ortega P, Escarpa A, de la Mata FJ. Sanz Del Olmo N, et al. Pharmaceutics. 2020 Jul 24;12(8):698. doi: 10.3390/pharmaceutics12080698. Pharmaceutics. 2020. PMID: 32722069 Free PMC article.
Their antioxidant activity has been studied by different techniques such as DPPH (2,2'-diphenyl-1-picrylhydrazyl) radical scavenging assay, FRAP assay (ferric reducing antioxidant power), and cyclic voltammetry. The antioxidant analysis showed that polyphenolic dendrimers …
Their antioxidant activity has been studied by different techniques such as DPPH (2,2'-diphenyl-1-picrylhydrazyl) radical scavenging assay, …
Plasma Non-Enzymatic Antioxidant Capacity (NEAC) in Relation to Dietary NEAC, Nutrient Antioxidants and Inflammation-Related Biomarkers.
Carrión-García CJ, Guerra-Hernández EJ, García-Villanova B, Serafini M, Sánchez MJ, Amiano P, Molina-Montes E. Carrión-García CJ, et al. Antioxidants (Basel). 2020 Apr 5;9(4):301. doi: 10.3390/antiox9040301. Antioxidants (Basel). 2020. PMID: 32260517 Free PMC article.
(1) Background: Little is known about the interlinkages between dietary and plasma non-enzymatic antioxidant capacity (D-NEAC and P-NEAC, respectively) and the body's antioxidant and inflammation response. Our aim was to explore these associations in 210 participants from …
(1) Background: Little is known about the interlinkages between dietary and plasma non-enzymatic antioxidant capacity (D-NEAC and P-N …
CD69 Plays a Beneficial Role in Ischemic Stroke by Dampening Endothelial Activation.
Brait VH, Miró-Mur F, Pérez-de-Puig I, Notario L, Hurtado B, Pedragosa J, Gallizioli M, Jiménez-Altayó F, Arbaizar-Rovirosa M, Otxoa-de-Amezaga A, Monteagudo J, Ferrer-Ferrer M, de la Rosa X, Bonfill-Teixidor E, Salas-Perdomo A, Hernández-Vidal A, Garcia-de-Frutos P, Lauzurica P, Planas AM. Brait VH, et al. Circ Res. 2019 Jan 18;124(2):279-291. doi: 10.1161/CIRCRESAHA.118.313818. Circ Res. 2019. PMID: 30582456 Free article.
We measured infarct volume, assessed neurological function, and studied CD69 expression, as well as platelet function, fibrin(ogen) deposition, and VWF (von Willebrand factor) expression in brain vessels and VWF content and activity in plasma, and performed the tail-vein bleeding …
We measured infarct volume, assessed neurological function, and studied CD69 expression, as well as platelet function, fibrin(ogen) depositi …
Pentacoordinate and hexacoordinate ferric hemes in acid medium: EPR, UV-Vis and CD studies of the giant extracellular hemoglobin of Glossoscolex paulistus.
Marmo Moreira L, Lima Poli A, Costa-Filho AJ, Imasato H. Marmo Moreira L, et al. Biophys Chem. 2006 Oct 20;124(1):62-72. doi: 10.1016/j.bpc.2006.05.030. Epub 2006 Jun 6. Biophys Chem. 2006. PMID: 16814451
Four new species were formed and coexist with the aquomethemoglobin upon acidification: (i) a "pure" low-spin hemichrome (Type II), also called hemichrome B, with an usual spin state (d(xy))(2)(d(xz),d(yz))(3); (ii) a strong g(max) hemichrome (Type I), also s …
Four new species were formed and coexist with the aquomethemoglobin upon acidification: (i) a "pure" low-spin hemichrome (Type II), also cal …
18 results