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Trigonelline and curcumin alone, but not in combination, counteract oxidative stress and inflammation and increase glycation product detoxification in the liver and kidney of mice with high-fat diet-induced obesity.
Costa MC, Lima TFO, Arcaro CA, Inacio MD, Batista-Duharte A, Carlos IZ, Spolidorio LC, Assis RP, Brunetti IL, Baviera AM. Costa MC, et al. Among authors: arcaro ca. J Nutr Biochem. 2020 Feb;76:108303. doi: 10.1016/j.jnutbio.2019.108303. Epub 2019 Nov 23. J Nutr Biochem. 2020. PMID: 31812909
Anabolic Effect of Insulin Therapy on the Bone: Osteoprotegerin and Osteocalcin Up-Regulation in Streptozotocin-Induced Diabetic Rats.
Bortolin RH, Freire Neto FP, Arcaro CA, Bezerra JF, da Silva FS, Ururahy MA, Souza KS, Lima VM, Luchessi AD, Lima FP, Lia Fook MV, da Silva BJ, Almeida MD, Abreu BJ, de Rezende LA, de Rezende AA. Bortolin RH, et al. Among authors: arcaro ca. Basic Clin Pharmacol Toxicol. 2017 Mar;120(3):227-234. doi: 10.1111/bcpt.12672. Epub 2016 Nov 24. Basic Clin Pharmacol Toxicol. 2017. PMID: 27651300 Free article.
Emodin, Physcion, and Crude Extract of Rhamnus sphaerosperma var. pubescens Induce Mixed Cell Death, Increase in Oxidative Stress, DNA Damage, and Inhibition of AKT in Cervical and Oral Squamous Carcinoma Cell Lines.
Moreira TF, Sorbo JM, Souza FO, Fernandes BC, Ocampos FMM, de Oliveira DMS, Arcaro CA, Assis RP, Barison A, Miguel OG, Baviera AM, Soares CP, Brunetti IL. Moreira TF, et al. Among authors: arcaro ca. Oxid Med Cell Longev. 2018 Jul 3;2018:2390234. doi: 10.1155/2018/2390234. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30057674 Free PMC article.
Curcumin Pharmacokinetic and Pharmacodynamic Evidences in Streptozotocin-Diabetic Rats Support the Antidiabetic Activity to Be via Metabolite(s).
Gutierres VO, Campos ML, Arcaro CA, Assis RP, Baldan-Cimatti HM, Peccinini RG, Paula-Gomes S, Kettelhut IC, Baviera AM, Brunetti IL. Gutierres VO, et al. Among authors: arcaro ca. Evid Based Complement Alternat Med. 2015;2015:678218. doi: 10.1155/2015/678218. Epub 2015 May 3. Evid Based Complement Alternat Med. 2015. PMID: 26064170 Free PMC article.