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Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin.
FASEB J. 2017 Jun;31(6):2507-2519. doi: 10.1096/fj.201601074R. Epub 2017 Feb 27.
FASEB J. 2017.
PMID: 28242772
Free PMC article.
G Protein-Coupled Receptors in cancer: biochemical interactions and drug design.
Audigier Y, Picault FX, Chaves-Almagro C, Masri B.
Audigier Y, et al. Among authors: chaves almagro c.
Prog Mol Biol Transl Sci. 2013;115:143-73. doi: 10.1016/B978-0-12-394587-7.00004-X.
Prog Mol Biol Transl Sci. 2013.
PMID: 23415094
Review.
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Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development.
Chaves-Almagro C, Auriau J, Dortignac A, Clerc P, Lulka H, Deleruyelle S, Projetti F, Nakhlé J, Frances A, Berta J, Gigoux V, Fourmy D, Dufresne M, Gomez-Brouchet A, Guillermet-Guibert J, Cordelier P, Knibiehler B, Jockers R, Valet P, Audigier Y, Masri B.
Chaves-Almagro C, et al.
Int J Mol Sci. 2022 Sep 13;23(18):10600. doi: 10.3390/ijms231810600.
Int J Mol Sci. 2022.
PMID: 36142542
Free PMC article.
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Tumour co-expression of apelin and its receptor is the basis of an autocrine loop involved in the growth of colon adenocarcinomas.
Picault FX, Chaves-Almagro C, Projetti F, Prats H, Masri B, Audigier Y.
Picault FX, et al. Among authors: chaves almagro c.
Eur J Cancer. 2014 Feb;50(3):663-74. doi: 10.1016/j.ejca.2013.11.017. Epub 2013 Dec 5.
Eur J Cancer. 2014.
PMID: 24316062
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