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BFD-22 a new potential inhibitor of BRAF inhibits the metastasis of B16F10 melanoma cells and simultaneously increased the tumor immunogenicity.
Ferreira AK, Pasqualoto KF, Kruyt FA, Palace-Berl F, Azevedo RA, Turra KM, Rodrigues CP, Ferreira AC, Salomón MA, de Sá Junior PL, Farias CF, Figueiredo CR, Tavares LC, Barbuto JA, Jorge SD. Ferreira AK, et al. Among authors: farias cf. Toxicol Appl Pharmacol. 2016 Mar 15;295:56-67. doi: 10.1016/j.taap.2016.02.008. Epub 2016 Feb 10. Toxicol Appl Pharmacol. 2016. PMID: 26876618
Antitumor activity of kielmeyera coriacea leaf constituents in experimental melanoma, tested in vitro and in vivo in syngeneic mice.
Figueiredo CR, Matsuo AL, Massaoka MH, Girola N, Azevedo RA, Rabaça AN, Farias CF, Pereira FV, Matias NS, Silva LP, Rodrigues EG, Lago JH, Travassos LR, Silva RM. Figueiredo CR, et al. Among authors: farias cf. Adv Pharm Bull. 2014 Oct;4(Suppl 1):429-36. doi: 10.5681/apb.2014.063. Epub 2014 Aug 25. Adv Pharm Bull. 2014. PMID: 25364658 Free PMC article.