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Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State.
Kurnik M, Sahin C, Andersen CB, Lorenzen N, Giehm L, Mohammad-Beigi H, Jessen CM, Pedersen JS, Christiansen G, Petersen SV, Staal R, Krishnamurthy G, Pitts K, Reinhart PH, Mulder FAA, Mente S, Hirst WD, Otzen DE. Kurnik M, et al. Cell Chem Biol. 2018 Nov 15;25(11):1389-1402.e9. doi: 10.1016/j.chembiol.2018.08.005. Epub 2018 Sep 6. Cell Chem Biol. 2018. PMID: 30197194 Free article.
How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro.
Lorenzen N, Nielsen SB, Yoshimura Y, Vad BS, Andersen CB, Betzer C, Kaspersen JD, Christiansen G, Pedersen JS, Jensen PH, Mulder FA, Otzen DE. Lorenzen N, et al. J Biol Chem. 2014 Aug 1;289(31):21299-310. doi: 10.1074/jbc.M114.554667. Epub 2014 Jun 6. J Biol Chem. 2014. PMID: 24907278 Free PMC article.
Falcarindiol Purified From Carrots Leads to Elevated Levels of Lipid Droplets and Upregulation of Peroxisome Proliferator-Activated Receptor-γ Gene Expression in Cellular Models.
Andersen CB, Runge Walther A, Pipó-Ollé E, Notabi MK, Juul S, Eriksen MH, Lovatt AL, Cowie R, Linnet J, Kobaek-Larsen M, El-Houri R, Andersen MØ, Hedegaard MAB, Christensen LP, Arnspang EC. Andersen CB, et al. Front Pharmacol. 2020 Aug 28;11:565524. doi: 10.3389/fphar.2020.565524. eCollection 2020. Front Pharmacol. 2020. PMID: 32982759 Free PMC article.
12 results