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Page 1
Advances in Mitochondrial Medicine and Translational Research.
Kuthethur R, Prasad K, Chakrabarty S, Prasada Kabekkodu S, Singh KK, Thangaraj K, Satyamoorthy K. Kuthethur R, et al. Mitochondrion. 2021 Aug 4:S1567-7249(21)00102-1. doi: 10.1016/j.mito.2021.08.001. Online ahead of print. Mitochondrion. 2021. PMID: 34363984
To systematically present the various findings in mitochondrial biology, the meeting was themed with specific aspects comprising (a) mitochondrial disorders: clinical & genomic perspectives, (b) mitochondria in cancer, (c) mitochondrial metabolism & disorders, and …
To systematically present the various findings in mitochondrial biology, the meeting was themed with specific aspects comprising (a) mitocho …
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.
Mlcochova P, Kemp SA, Dhar MS, Papa G, Meng B, Ferreira IATM, Datir R, Collier DA, Albecka A, Singh S, Pandey R, Brown J, Zhou J, Goonawardane N, Mishra S, Whittaker C, Mellan T, Marwal R, Datta M, Sengupta S, Ponnusamy K, Radhakrishnan VS, Abdullahi A, Charles O, Chattopadhyay P, Devi P, Caputo D, Peacock T, Wattal C, Goel N, Satwik A, Vaishya R, Agarwal M; Indian SARS-CoV-2 Genomics Consortium (INSACOG); Genotype to Phenotype Japan (G2P-Japan) Consortium; CITIID-NIHR BioResource COVID-19 Collaboration; Mavousian A, Lee JH, Bassi J, Silacci-Fegni C, Saliba C, Pinto D, Irie T, Yoshida I, Hamilton WL, Sato K, Bhatt S, Flaxman S, James LC, Corti D, Piccoli L, Barclay WS, Rakshit P, Agrawal A, Gupta RK. Mlcochova P, et al. Nature. 2021 Nov;599(7883):114-119. doi: 10.1038/s41586-021-03944-y. Epub 2021 Sep 6. Nature. 2021. PMID: 34488225 Free PMC article.
Natural killer cell therapy potentially enhances the antitumor effects of bevacizumab plus irinotecan in a glioblastoma mouse model.
Tran TA, Kim YH, Duong TH, Thangaraj J, Chu TH, Jung S, Kim IY, Moon KS, Kim YJ, Lee TK, Lee CW, Yun H, Lee JJ, Lee HJ, Lee KH, Jung TY. Tran TA, et al. Front Immunol. 2023 Jan 10;13:1009484. doi: 10.3389/fimmu.2022.1009484. eCollection 2022. Front Immunol. 2023. PMID: 36703992 Free PMC article.
The therapeutic effect of different injected NK cell routes and numbers combined with the different doses of Bev and Iri was confirmed according to tumor size and survival in the subcutaneous (s.c) and intracranial (i.c) U87 xenograft NOD/SCID IL-12Rgamma(null) mous …
The therapeutic effect of different injected NK cell routes and numbers combined with the different doses of Bev and Iri was confirmed accor …
Novel TCAP mutation c.32C>A causing limb girdle muscular dystrophy 2G.
Francis A, Sunitha B, Vinodh K, Polavarapu K, Katkam SK, Modi S, Bharath MM, Gayathri N, Nalini A, Thangaraj K. Francis A, et al. PLoS One. 2014 Jul 23;9(7):e102763. doi: 10.1371/journal.pone.0102763. eCollection 2014. PLoS One. 2014. PMID: 25055047 Free PMC article.
Genetic analysis revealed a novel nonsense homozygous mutation c.32C>A, p.(Ser11*) in three patients of a consanguineous family and an 8 bp homozygous duplication c.26_33dupAGGTGTCG, p....We could not find any functionally significant TCAP mutation in the remaini …
Genetic analysis revealed a novel nonsense homozygous mutation c.32C>A, p.(Ser11*) in three patients of a consanguineous family an …
c.*84G>A Mutation in CETP Is Associated with Coronary Artery Disease in South Indians.
Ganesan M, Nizamuddin S, Katkam SK, Kumaraswami K, Hosad UK, Lobo LL, Kutala VK, Thangaraj K. Ganesan M, et al. PLoS One. 2016 Oct 21;11(10):e0164151. doi: 10.1371/journal.pone.0164151. eCollection 2016. PLoS One. 2016. PMID: 27768712 Free PMC article.
RESULTS AND DISCUSSION: Our analysis revealed a total of 13 variations. Of these, one3'UTRvariant rs1801706 (c.*84G>A) was significantly associated with CAD (genotype association test: OR = 2.16, 95% CI: 1.50-3.10, p = 1.88x10-5 and allelic association test: OR = 1.92, …
RESULTS AND DISCUSSION: Our analysis revealed a total of 13 variations. Of these, one3'UTRvariant rs1801706 (c.*84G>A) was signifi …
Ocean warming and acidification affect the transitional C:N:P ratio and macromolecular accumulation in the harmful raphidophyte Heterosigma akashiwo.
Thangaraj S, Sun J. Thangaraj S, et al. Commun Biol. 2023 Feb 6;6(1):151. doi: 10.1038/s42003-023-04524-8. Commun Biol. 2023. PMID: 36747020 Free PMC article.
However, how this species physically and metabolically modifies transitional C:N:P ratio and macromolecule accumulation is unknown. Considering 1st, 10th, and 20th culture generations under present (low-temperature; low-carbon-dioxide [LTLC] 21 C; pCO(2) 400 ppm) an …
However, how this species physically and metabolically modifies transitional C:N:P ratio and macromolecule accumulation is unknown. C …
Advances in mitochondrial medicine and translational research.
Kuthethur R, Prasad K, Chakrabarty S, Kabekkodu SP, Singh KK, Thangaraj K, Satyamoorthy K. Kuthethur R, et al. Mitochondrion. 2021 Nov;61:62-68. doi: 10.1016/j.mito.2021.09.008. Epub 2021 Sep 24. Mitochondrion. 2021. PMID: 34571249
To systematically present the various findings in mitochondrial biology, the meeting was themed with specific aspects comprising (a) mitochondrial disorders: clinical & genomic perspectives, (b) mitochondria in cancer, (c) mitochondrial metabolism & disorders, and …
To systematically present the various findings in mitochondrial biology, the meeting was themed with specific aspects comprising (a) mitocho …
c.620C>T mutation in GATA4 is associated with congenital heart disease in South India.
Mattapally S, Nizamuddin S, Murthy KS, Thangaraj K, Banerjee SK. Mattapally S, et al. BMC Med Genet. 2015 Feb 18;16:7. doi: 10.1186/s12881-015-0152-7. BMC Med Genet. 2015. PMID: 25928801 Free PMC article.
Interestingly, one promoter mutation (-490 to 100 bp) i.e., 620 C>T (rs61277615, p-value = 0.008514), one splice junction mutation (G>A rs73203482; p-value = 9.6e-3, OR = 6.508) and one intronic mutation rs4841587 (p-value = 4.6e-3, OR = 4.758) were the most signific …
Interestingly, one promoter mutation (-490 to 100 bp) i.e., 620 C>T (rs61277615, p-value = 0.008514), one splice junction mutation …
125 results