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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 1
1950 1
1951 2
1952 1
1957 1
1960 1
1963 2
1966 1
1967 4
1968 1
1969 1
1970 1
1971 2
1972 2
1973 1
1974 1
1976 1
1977 2
1979 4
1980 1
1981 5
1982 1
1983 5
1984 4
1985 2
1986 3
1987 6
1988 6
1989 11
1990 13
1991 14
1992 21
1993 19
1994 20
1995 20
1996 22
1997 23
1998 22
1999 28
2000 37
2001 33
2002 41
2003 47
2004 58
2005 78
2006 81
2007 77
2008 79
2009 73
2010 81
2011 86
2012 82
2013 101
2014 122
2015 135
2016 159
2017 184
2018 155
2019 160
2020 178
2021 219
2022 187
2023 152
2024 69

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2,623 results

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Page 1
Antiviral Profiling of C-18- or C-19-Functionalized Semisynthetic Abietane Diterpenoids.
González-Cardenete MA, Hamulić D, Miquel-Leal FJ, González-Zapata N, Jimenez-Jarava OJ, Brand YM, Restrepo-Mendez LC, Martinez-Gutierrez M, Betancur-Galvis LA, Marín ML. González-Cardenete MA, et al. J Nat Prod. 2022 Aug 26;85(8):2044-2051. doi: 10.1021/acs.jnatprod.2c00464. Epub 2022 Aug 15. J Nat Prod. 2022. PMID: 35969814 Free PMC article. Review.
Several natural and semisynthetic abietane-type diterpenoids have shown important antiviral activities. In this study, a biological evaluation of a number of either C-18- or C-19-functionalized known semisynthetic abietanes against Zika virus, Dengue virus, Herpes v …
Several natural and semisynthetic abietane-type diterpenoids have shown important antiviral activities. In this study, a biological evaluati …
The c-Abl/p73 pathway induces neurodegeneration in a Parkinson's disease model.
Marín T, Valls C, Jerez C, Huerta T, Elgueta D, Vidal RL, Alvarez AR, Cancino GI. Marín T, et al. IBRO Neurosci Rep. 2022 Oct 19;13:378-387. doi: 10.1016/j.ibneur.2022.10.006. eCollection 2022 Dec. IBRO Neurosci Rep. 2022. PMID: 36590096 Free PMC article.
One pro-apoptotic pathway associated with several neurodegenerative diseases is the tyrosine kinase c-Abl and its target p73. Here, we evaluated the contribution of c-Abl and p73 in the degeneration of dopaminergic neurons induced by the neurotoxin 6-hydroxydopamine …
One pro-apoptotic pathway associated with several neurodegenerative diseases is the tyrosine kinase c-Abl and its target p73. Here, w …
c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.
Marín T, Dulcey AE, Campos F, de la Fuente C, Acuña M, Castro J, Pinto C, Yañez MJ, Cortez C, McGrath DW, Sáez PJ, Gorshkov K, Zheng W, Southall N, Carmo-Fonseca M, Marugán J, Alvarez AR, Zanlungo S. Marín T, et al. Front Cell Dev Biol. 2022 Mar 18;10:844297. doi: 10.3389/fcell.2022.844297. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35399514 Free PMC article.
Interestingly, this kinase is also activated in other lysosomal neurodegenerative disorders. Here, we describe that c-Abl activation contributes to the mechanisms of neuronal damage and death in NPA disease. Our data demonstrate that: 1) c-Abl is activated in-vitro …
Interestingly, this kinase is also activated in other lysosomal neurodegenerative disorders. Here, we describe that c-Abl activation …
Relevant Fusarium Mycotoxins in Malt and Beer.
Pascari X, Marin S, Ramos AJ, Sanchis V. Pascari X, et al. Foods. 2022 Jan 17;11(2):246. doi: 10.3390/foods11020246. Foods. 2022. PMID: 35053978 Free PMC article. Review.
Studies show that germination is the malting step that can lead to a significant increase in the level of all Fusarium mycotoxins. The first step of mashing (45 C) has been proved to possess the most significant impact in the transfer of hydrophilic toxins from the grist i …
Studies show that germination is the malting step that can lead to a significant increase in the level of all Fusarium mycotoxins. The first …
Advances in sepsis biomarkers.
Marin MJ, van Wijk XMR, Chambliss AB. Marin MJ, et al. Adv Clin Chem. 2024;119:117-166. doi: 10.1016/bs.acc.2024.02.003. Epub 2024 Feb 15. Adv Clin Chem. 2024. PMID: 38514209
This chapter reviews (1) the basic principles of infectious diseases, pathophysiology and current definition of sepsis, (2) established sepsis biomarkers such lactate, procalcitonin and C-reactive protein, (3) novel, newly regulatory-cleared/approved biomarkers, such as as …
This chapter reviews (1) the basic principles of infectious diseases, pathophysiology and current definition of sepsis, (2) established seps …
Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability.
Erdem A, Marin S, Pereira-Martins DA, Geugien M, Cunningham A, Pruis MG, Weinhäuser I, Gerding A, Bakker BM, Wierenga ATJ, Rego EM, Huls G, Cascante M, Schuringa JJ. Erdem A, et al. Nat Commun. 2022 Apr 19;13(1):2013. doi: 10.1038/s41467-022-29639-0. Nat Commun. 2022. PMID: 35440568 Free PMC article.
While inhibition of ETC complex II enhances apoptosis in FLT3-ITD(+) AML, cells also quickly adapt by importing lactate from the extracellular microenvironment. (13)C(3)-labelled lactate metabolic flux analyses reveal that AML cells use lactate as a fuel for mitochondrial …
While inhibition of ETC complex II enhances apoptosis in FLT3-ITD(+) AML, cells also quickly adapt by importing lactate from the extracellul …
The ouabain-insensitive sodium pump.
Proverbio F, Marín R, Proverbio T. Proverbio F, et al. Comp Biochem Physiol A Comp Physiol. 1991;99(3):279-83. doi: 10.1016/0300-9629(91)90002-t. Comp Biochem Physiol A Comp Physiol. 1991. PMID: 1678327 Review. No abstract available.
2,623 results