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Immune modulation by the hepatitis C virus core protein.
Fernández-Ponce C, Dominguez-Villar M, Muñoz-Miranda JP, Arbulo-Echevarria MM, Litrán R, Aguado E, García-Cozar F. Fernández-Ponce C, et al. J Viral Hepat. 2017 May;24(5):350-356. doi: 10.1111/jvh.12675. Epub 2017 Feb 2. J Viral Hepat. 2017. PMID: 28092420 Review.
Hepatitis C virus (HCV) infection is currently the most important cause of chronic viral hepatitis in the world and one of the most frequent indications for liver transplantation. ...
Hepatitis C virus (HCV) infection is currently the most important cause of chronic viral hepatitis in the world and one of the most f …
Ultrastructural Localization and Molecular Associations of HCV Capsid Protein in Jurkat T Cells.
Fernández-Ponce C, Durán-Ruiz MC, Narbona-Sánchez I, Muñoz-Miranda JP, Arbulo-Echevarria MM, Serna-Sanz A, Baumann C, Litrán R, Aguado E, Bloch W, García-Cozar F. Fernández-Ponce C, et al. Front Microbiol. 2018 Jan 4;8:2595. doi: 10.3389/fmicb.2017.02595. eCollection 2017. Front Microbiol. 2018. PMID: 29354102 Free PMC article.
Hepatitis C virus core protein is a highly basic viral protein that multimerizes with itself to form the viral capsid. ...We found that in Jurkat T cells, Hepatitis C virus core protein mostly localizes in the nucleus and specifically in the nucleolus. ...
Hepatitis C virus core protein is a highly basic viral protein that multimerizes with itself to form the viral capsid. ...We found th …
The effects of mango leaf extract during adolescence and adulthood in a rat model of schizophrenia.
Garcia-Partida JA, Torres-Sanchez S, MacDowell K, Fernández-Ponce MT, Casas L, Mantell C, Soto-Montenegro ML, Romero-Miguel D, Lamanna-Rama N, Leza JC, Desco M, Berrocoso E. Garcia-Partida JA, et al. Front Pharmacol. 2022 Jul 26;13:886514. doi: 10.3389/fphar.2022.886514. eCollection 2022. Front Pharmacol. 2022. PMID: 35959428 Free PMC article.
Hence, this study set-out to evaluate the effect of mango leaf extract (MLE) in a model of schizophrenia based on maternal immune activation, in which Poly I:C (4 mg/kg) is administered intravenously to pregnant rats. Young adult (postnatal day 60-70) or adolescent (postna …
Hence, this study set-out to evaluate the effect of mango leaf extract (MLE) in a model of schizophrenia based on maternal immune activation …
Green extraction of antioxidants from different varieties of red grape pomace.
Otero-Pareja MJ, Casas L, Fernández-Ponce MT, Mantell C, Martínez de la Ossa EJ. Otero-Pareja MJ, et al. Molecules. 2015 May 26;20(6):9686-702. doi: 10.3390/molecules20069686. Molecules. 2015. PMID: 26016554 Free PMC article.
The best conditios for PLE obtained from the experimental design and kinetic study were 50% ethanol/water as the pressurized solvent at 90 bar, 120 C, a flow rate of 5 g/min and, an extraction time of 90 min. A statistical analysis of variance has been performed and it was …
The best conditios for PLE obtained from the experimental design and kinetic study were 50% ethanol/water as the pressurized solvent at 90 b …
Up-regulation of FOXP3 and induction of suppressive function in CD4+ Jurkat T-cells expressing hepatitis C virus core protein.
Dominguez-Villar M, Fernandez-Ponce C, Munoz-Suano A, Gomez E, Rodríguez-Iglesias M, Garcia-Cozar F. Dominguez-Villar M, et al. Clin Sci (Lond). 2012 Jul;123(1):15-27. doi: 10.1042/CS20110631. Clin Sci (Lond). 2012. PMID: 22214248
HCV (hepatitis C virus) infection is a serious health care problem that affects more than 170 million people worldwide. ...
HCV (hepatitis C virus) infection is a serious health care problem that affects more than 170 million people worldwide. ...
Usage of supercritical fluid techniques to obtain bioactive alkaloid-rich extracts from cherimoya peel and leaves: extract profiles and their correlation with antioxidant properties and acetylcholinesterase and α-glucosidase inhibitory activities.
Galarce-Bustos O , Fernández-Ponce MT , Montes A , Pereyra C , Casas L , Mantell C , Aranda M . Galarce-Bustos O , et al. Food Funct. 2020 May 1;11(5):4224-4235. doi: 10.1039/d0fo00342e. Epub 2020 Apr 30. Food Funct. 2020. PMID: 32353090
The extracts were obtained from the peel and leaves using the following optimal conditions: 100 bar of pressure, 75 C and 15% methanol as co-solvent. High antioxidant capacity (5304.23 73.60 to 21 705.20 1069.31 mumol Trolox equivalent per 100 g), and acetylcholinesterase …
The extracts were obtained from the peel and leaves using the following optimal conditions: 100 bar of pressure, 75 C and 15% methano …
Potential Use of Annona Genus Plants Leaf Extracts to Produce Bioactive Transdermal Patches by Supercritical Solvent Impregnation.
Fernández Ponce MT, Cejudo Bastante C, Casas Cardoso L, Mantell C, Martínez de la Ossa EJ, Pereyra C. Fernández Ponce MT, et al. Antioxidants (Basel). 2021 Jul 27;10(8):1196. doi: 10.3390/antiox10081196. Antioxidants (Basel). 2021. PMID: 34439444 Free PMC article.
The optimal impregnation conditions of ALE were established at 55 C and 300 bar which led to obtained transdermal patches with antioxidant and antimicrobial capacity. ...
The optimal impregnation conditions of ALE were established at 55 C and 300 bar which led to obtained transdermal patches with antiox …
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