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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1993 1
2007 1
2008 1
2011 2
2012 1
2013 3
2014 3
2015 3
2017 3
2018 2
2019 2
2020 3
2021 5
2022 8
2023 2
2024 0

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37 results

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Page 1
Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.
Soria JC, Ohe Y, Vansteenkiste J, Reungwetwattana T, Chewaskulyong B, Lee KH, Dechaphunkul A, Imamura F, Nogami N, Kurata T, Okamoto I, Zhou C, Cho BC, Cheng Y, Cho EK, Voon PJ, Planchard D, Su WC, Gray JE, Lee SM, Hodge R, Marotti M, Rukazenkov Y, Ramalingam SS; FLAURA Investigators. Soria JC, et al. N Engl J Med. 2018 Jan 11;378(2):113-125. doi: 10.1056/NEJMoa1713137. Epub 2017 Nov 18. N Engl J Med. 2018. PMID: 29151359 Free article. Clinical Trial.
Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC.
Ramalingam SS, Vansteenkiste J, Planchard D, Cho BC, Gray JE, Ohe Y, Zhou C, Reungwetwattana T, Cheng Y, Chewaskulyong B, Shah R, Cobo M, Lee KH, Cheema P, Tiseo M, John T, Lin MC, Imamura F, Kurata T, Todd A, Hodge R, Saggese M, Rukazenkov Y, Soria JC; FLAURA Investigators. Ramalingam SS, et al. N Engl J Med. 2020 Jan 2;382(1):41-50. doi: 10.1056/NEJMoa1913662. Epub 2019 Nov 21. N Engl J Med. 2020. PMID: 31751012 Free article. Clinical Trial.
Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation.
Sacher A, LoRusso P, Patel MR, Miller WH Jr, Garralda E, Forster MD, Santoro A, Falcon A, Kim TW, Paz-Ares L, Bowyer S, de Miguel M, Han SW, Krebs MG, Lee JS, Cheng ML, Arbour K, Massarelli E, Choi Y, Shi Z, Mandlekar S, Lin MT, Royer-Joo S, Chang J, Dharia NV, Schutzman JL, Desai J; GO42144 Investigator and Study Group. Sacher A, et al. N Engl J Med. 2023 Aug 24;389(8):710-721. doi: 10.1056/NEJMoa2303810. N Engl J Med. 2023. PMID: 37611121 Free article. Clinical Trial.
Trial of Prasinezumab in Early-Stage Parkinson's Disease.
Pagano G, Taylor KI, Anzures-Cabrera J, Marchesi M, Simuni T, Marek K, Postuma RB, Pavese N, Stocchi F, Azulay JP, Mollenhauer B, López-Manzanares L, Russell DS, Boyd JT, Nicholas AP, Luquin MR, Hauser RA, Gasser T, Poewe W, Ricci B, Boulay A, Vogt A, Boess FG, Dukart J, D'Urso G, Finch R, Zanigni S, Monnet A, Pross N, Hahn A, Svoboda H, Britschgi M, Lipsmeier F, Volkova-Volkmar E, Lindemann M, Dziadek S, Holiga Š, Rukina D, Kustermann T, Kerchner GA, Fontoura P, Umbricht D, Doody R, Nikolcheva T, Bonni A; PASADENA Investigators; Prasinezumab Study Group. Pagano G, et al. N Engl J Med. 2022 Aug 4;387(5):421-432. doi: 10.1056/NEJMoa2202867. N Engl J Med. 2022. PMID: 35921451 Clinical Trial.
Electrochemically Initiated Synthesis of Methanesulfonic Acid.
Britschgi J, Kersten W, Waldvogel SR, Schüth F. Britschgi J, et al. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202209591. doi: 10.1002/anie.202209591. Epub 2022 Aug 31. Angew Chem Int Ed Engl. 2022. PMID: 35972467 Free PMC article.
The highest concentration of 3.7 M (approximately 62 % yield) at 97 % selectivity was reached with a stepped electric current program at 6.25-12.5 mA cm(-2) , 70 C and 90 bar methane pressure in 22 hours. We present a novel, electrochemical method to produce methanesulfoni …
The highest concentration of 3.7 M (approximately 62 % yield) at 97 % selectivity was reached with a stepped electric current program at 6.2 …
Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies.
Moors TE, Mona D, Luehe S, Duran-Pacheco G, Spycher L, Mundigl O, Kaluza K, Huber S, Hug MN, Kremer T, Ritter M, Dziadek S, Dernick G, van de Berg WDJ, Britschgi M. Moors TE, et al. Acta Neuropathol Commun. 2022 Jun 3;10(1):82. doi: 10.1186/s40478-022-01382-z. Acta Neuropathol Commun. 2022. PMID: 35659116 Free PMC article.
Based on immunostainings and biochemical analyses, certain post-translationally modified alpha-synuclein (aSyn) variants, including C-terminally truncated (CTT) and Serine-129 phosphorylated (pSer129) aSyn, are proposed to be involved in the pathogenesis of synucleinopathi …
Based on immunostainings and biochemical analyses, certain post-translationally modified alpha-synuclein (aSyn) variants, including C …
Phylogenetic analysis of a natural marine bacterioplankton population by rRNA gene cloning and sequencing.
Britschgi TB, Giovannoni SJ. Britschgi TB, et al. Appl Environ Microbiol. 1991 Jun;57(6):1707-13. doi: 10.1128/aem.57.6.1707-1713.1991. Appl Environ Microbiol. 1991. PMID: 1714704 Free PMC article.
In addition to 16S rRNA genes from the marine Synechococcus cluster and the previously identified but uncultivated microbial group, the SAR11 cluster [S. J. Giovannoni, T. B. Britschgi, C. L. Moyer, and K. G. Field. Nature (London) 345:60-63], two new gene classes w …
In addition to 16S rRNA genes from the marine Synechococcus cluster and the previously identified but uncultivated microbial group, the SAR1 …
Phylogenetic diversity of subsurface marine microbial communities from the Atlantic and Pacific Oceans.
Fuhrman JA, McCallum K, Davis AA. Fuhrman JA, et al. Appl Environ Microbiol. 1993 May;59(5):1294-302. doi: 10.1128/aem.59.5.1294-1302.1993. Appl Environ Microbiol. 1993. PMID: 7685997 Free PMC article.
We report 15 clones related to clone SAR 11 found earlier near Bermuda (S. J. Giovannoni, T. B. Britschgi, C. L. Moyer, and K. G. Field, Nature [London] 345:60-63, 1990), 11 related to marine cyanobacteria, 9 clustered in a group affiliated with gram-positive bacter …
We report 15 clones related to clone SAR 11 found earlier near Bermuda (S. J. Giovannoni, T. B. Britschgi, C. L. Moyer, and K. …
Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma.
Planas-Paz L, Pliego-Mendieta A, Hagedorn C, Aguilera-Garcia D, Haberecker M, Arnold F, Herzog M, Bankel L, Guggenberger R, Steiner S, Chen Y, Kahraman A, Zoche M, Rubin MA, Moch H, Britschgi C, Pauli C. Planas-Paz L, et al. EMBO Mol Med. 2023 Apr 11;15(4):e16863. doi: 10.15252/emmm.202216863. Epub 2023 Feb 13. EMBO Mol Med. 2023. PMID: 36779660 Free PMC article.
Closing escape routes: inhibition of IL-8 signaling enhances the anti-tumor efficacy of PI3K inhibitors.
Juvekar A, Wulf GM. Juvekar A, et al. Breast Cancer Res. 2013 Apr 8;15(2):308. doi: 10.1186/bcr3400. Breast Cancer Res. 2013. PMID: 23566381 Free PMC article.
However, as is increasingly observed with inhibitors of cell signaling, there appear to be mechanisms of primary and secondary resistance. Britschgi and colleagues report that compensatory activation of the IL-8 signaling axis is a mechanism of primary resistance to PI3K i …
However, as is increasingly observed with inhibitors of cell signaling, there appear to be mechanisms of primary and secondary resistance. …
37 results