Junctional adhesion molecule C (JAM-C) dimerization aids cancer cell migration and metastasis.
Garrido-Urbani S, Vonlaufen A, Stalin J, De Grandis M, Ropraz P, Jemelin S, Bardin F, Scheib H, Aurrand-Lions M, Imhof BA.
Garrido-Urbani S, et al.
Biochim Biophys Acta Mol Cell Res. 2018 Apr;1865(4):638-649. doi: 10.1016/j.bbamcr.2018.01.008. Epub 2018 Jan 31.
Biochim Biophys Acta Mol Cell Res. 2018.
PMID: 29378216
Free article.
We previously showed that the homodimerization site (E66) in JAM-C is also involved in JAM-B binding. Here we show that neoexpression of JAM-C in a JAM-C-negative carcinoma cell line induced loss of adhesive property and pro-metastatic capacities. ...Carcinom …
We previously showed that the homodimerization site (E66) in JAM-C is also involved in JAM-B binding. Here we show that neoexpression …