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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1973 1
1975 1
1976 3
1977 6
1978 3
1979 2
1980 3
1981 2
1982 6
1983 3
1984 4
1985 2
1986 3
1988 4
1989 3
1990 7
1991 9
1992 12
1993 4
1994 8
1995 13
1996 11
1997 16
1998 11
1999 15
2000 16
2001 15
2002 13
2003 25
2004 17
2005 23
2006 24
2007 11
2008 21
2009 23
2010 21
2011 22
2012 32
2013 26
2014 37
2015 48
2016 60
2017 53
2018 44
2019 25
2020 29
2021 21
2022 24
2023 25
2024 4

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759 results

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Page 1
The protective role of conjunctival goblet cell mucin sialylation.
Matsuzawa M, Ando T, Fukase S, Kimura M, Kume Y, Ide T, Izawa K, Kaitani A, Hara M, Nakamura E, Kamei A, Matsuda A, Nakano N, Maeda K, Tada N, Ogawa H, Okumura K, Murakami A, Ebihara N, Kitaura J. Matsuzawa M, et al. Nat Commun. 2023 Mar 17;14(1):1417. doi: 10.1038/s41467-023-37101-y. Nat Commun. 2023. PMID: 36932081 Free PMC article.
Here we show that human and mouse conjunctival goblet cell mucins have Alcian blue-detectable sialic acids, but not sulfates in the steady state. Interestingly, Balb/c mouse strain lacks this sialylation due to a point mutation in a sialyltransferase gene, St6galnac1, whic …
Here we show that human and mouse conjunctival goblet cell mucins have Alcian blue-detectable sialic acids, but not sulfates in the steady s …
Imeglimin prevents visceral hypersensitivity and colonic hyperpermeability in irritable bowel syndrome rat model.
Nozu T, Miyagishi S, Ishioh M, Takakusaki K, Okumura T. Nozu T, et al. J Pharmacol Sci. 2023 Sep;153(1):26-30. doi: 10.1016/j.jphs.2023.07.002. Epub 2023 Jul 7. J Pharmacol Sci. 2023. PMID: 37524451 Free article.
Imeglimin blocked lipopolysaccharide- or CRF-induced visceral hypersensitivity and colonic hyperpermeability. These effects were prevented by compound C or naloxone. These results suggest that imeglimin may be effective for the treatment of IBS by improved visceral sensati …
Imeglimin blocked lipopolysaccharide- or CRF-induced visceral hypersensitivity and colonic hyperpermeability. These effects were prevented b …
Injection of Cultured Cells with a ROCK Inhibitor for Bullous Keratopathy.
Kinoshita S, Koizumi N, Ueno M, Okumura N, Imai K, Tanaka H, Yamamoto Y, Nakamura T, Inatomi T, Bush J, Toda M, Hagiya M, Yokota I, Teramukai S, Sotozono C, Hamuro J. Kinoshita S, et al. N Engl J Med. 2018 Mar 15;378(11):995-1003. doi: 10.1056/NEJMoa1712770. N Engl J Med. 2018. PMID: 29539291 Free article. Clinical Trial.
Secondary outcomes were a corneal thickness of less than 630 mum and an improvement in best corrected visual acuity equivalent to two lines or more on a Landolt C eye chart at 24 weeks after cell injection. RESULTS: At 24 weeks after cell injection, we recorded a CEC densi …
Secondary outcomes were a corneal thickness of less than 630 mum and an improvement in best corrected visual acuity equivalent to two lines …
Hereditary Fibrinogen Aα-Chain Amyloidosis in Asia: Clinical and Molecular Characteristics.
Yazaki M, Yoshinaga T, Sekijima Y, Kametani F, Okumura N. Yazaki M, et al. Int J Mol Sci. 2018 Jan 22;19(1):320. doi: 10.3390/ijms19010320. Int J Mol Sci. 2018. PMID: 29361747 Free PMC article. Review.
In molecular features in Asian Aalpha-chain amyloidosis, the most common variant, E526V, was found in only one Chinese kindred, and other four kindred each had a different variant, which have not been identified in other countries. These variants are located in the C-termi …
In molecular features in Asian Aalpha-chain amyloidosis, the most common variant, E526V, was found in only one Chinese kindred, and other fo …
CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization.
Watanabe R, Hara M, Okumura EI, Hervé S, Fachinetti D, Ariyoshi M, Fukagawa T. Watanabe R, et al. J Cell Biol. 2019 Dec 2;218(12):4042-4062. doi: 10.1083/jcb.201907006. Epub 2019 Nov 1. J Cell Biol. 2019. PMID: 31676716 Free PMC article.
As CENP-C is a hub protein for kinetochore assembly, it is critical to address how the CENP-A-CENP-C interaction is regulated during cell cycle progression. To address this question, we investigated the CENP-C C-terminal region, including a conserved C …
As CENP-C is a hub protein for kinetochore assembly, it is critical to address how the CENP-A-CENP-C interaction is regulated …
Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure.
Kanematsu T, Oue K, Okumura T, Harada K, Yamawaki Y, Asano S, Mizokami A, Irifune M, Hirata M. Kanematsu T, et al. J Oral Biosci. 2019 Jun;61(2):65-72. doi: 10.1016/j.job.2019.04.002. Epub 2019 May 15. J Oral Biosci. 2019. PMID: 31109860 Review.
HIGHLIGHT: In our previous study on intracellular signaling of phospholipase C-related catalytically inactive protein (PRIP), we generated and analyzed Prip-double knockout (Prip-DKO) mice. ...
HIGHLIGHT: In our previous study on intracellular signaling of phospholipase C-related catalytically inactive protein (PRIP), we gene …
759 results