PD 122860: a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties.
Haleen SJ, Steffen RP, Sircar I, Major TC, Taylor MD, Pugsley TA, Weishaar RE.
Haleen SJ, et al.
J Pharmacol Exp Ther. 1989 Jul;250(1):22-30.
J Pharmacol Exp Ther. 1989.
PMID: 2473188
PD 122860 selectively relaxed potassium-contracted aortic rings and inhibited [3H]nitrendipine binding to rat brain membranes, suggesting that the vasodilator activity of PD 122860 is due to Ca++ channel blockade. ...
PD 122860 selectively relaxed potassium-contracted aortic rings and inhibited [3H]nitrendipine binding to rat brain membranes, sugges …