Brian W. Bigger - Search Results

Year	Number of Results
2004	1
2005	1
2006	1
2007	1
2009	3
2010	5
2011	4
2012	6
2013	7
2014	6
2015	5
2016	2
2017	3
2018	9
2019	9
2020	4
2021	3
2022	2
2023	6
2024	3

1

Delivering gene therapy for mucopolysaccharide diseases.

Wood SR, Bigger BW. Wood SR, et al. Among authors: bigger bw. Front Mol Biosci. 2022 Sep 12;9:965089. doi: 10.3389/fmolb.2022.965089. eCollection 2022. Front Mol Biosci. 2022. PMID: 36172050 Free PMC article. Review.

2

Anatomical changes and pathophysiology of the brain in mucopolysaccharidosis disorders.

Bigger BW, Begley DJ, Virgintino D, Pshezhetsky AV. Bigger BW, et al. Mol Genet Metab. 2018 Dec;125(4):322-331. doi: 10.1016/j.ymgme.2018.08.003. Epub 2018 Aug 10. Mol Genet Metab. 2018. PMID: 30145178 Free article. Review.

3

The role of innate immunity in mucopolysaccharide diseases.

Parker H, Bigger BW. Parker H, et al. Among authors: bigger bw. J Neurochem. 2019 Mar;148(5):639-651. doi: 10.1111/jnc.14632. Epub 2018 Dec 13. J Neurochem. 2019. PMID: 30451296 Free PMC article. Review.

4

Intraparenchymal convection enhanced delivery of AAV in sheep to treat Mucopolysaccharidosis IIIC.

O'Leary C, Forte G, Mitchell NL, Youshani AS, Dyer A, Wellby MP, Russell KN, Murray SJ, Jolinon N, Jones SA, Stacey K, Davis DM, Henckaerts E, Palmer DN, Kamaly-Asl I, Bigger BW. O'Leary C, et al. Among authors: bigger bw. J Transl Med. 2023 Jul 5;21(1):437. doi: 10.1186/s12967-023-04208-1. J Transl Med. 2023. PMID: 37407981 Free PMC article.

5

The role of antibodies in enzyme treatments and therapeutic strategies.

Bigger BW, Saif M, Linthorst GE. Bigger BW, et al. Best Pract Res Clin Endocrinol Metab. 2015 Mar;29(2):183-94. doi: 10.1016/j.beem.2015.01.006. Epub 2015 Jan 24. Best Pract Res Clin Endocrinol Metab. 2015. PMID: 25987172 Review.

6

Delivering Hematopoietic Stem Cell Gene Therapy Treatments for Neurological Lysosomal Diseases.

Holley RJ, Wood SR, Bigger BW. Holley RJ, et al. Among authors: bigger bw. ACS Chem Neurosci. 2019 Jan 16;10(1):18-20. doi: 10.1021/acschemneuro.8b00408. Epub 2018 Aug 23. ACS Chem Neurosci. 2019. PMID: 30136572 Review.

7

Dual Purpose Vectors for Rare Neurological Diseases.

Bigger BW. Bigger BW. Mol Ther. 2020 Oct 7;28(10):2104-2105. doi: 10.1016/j.ymthe.2020.09.017. Epub 2020 Sep 18. Mol Ther. 2020. PMID: 32949496 Free PMC article. No abstract available.

8

Current and Future Treatment of Mucopolysaccharidosis (MPS) Type II: Is Brain-Targeted Stem Cell Gene Therapy the Solution for This Devastating Disorder?

Horgan C, Jones SA, Bigger BW, Wynn R. Horgan C, et al. Among authors: bigger bw. Int J Mol Sci. 2022 Apr 27;23(9):4854. doi: 10.3390/ijms23094854. Int J Mol Sci. 2022. PMID: 35563245 Free PMC article. Review.

9

Sustained long-term disease correction in a murine model of MPSII following stem cell gene therapy.

Ellison S, Liao A, Gleitz HFE, Parker H, Booth L, Robinson J, Wood S, Taylor J, Holley R, Bigger BW. Ellison S, et al. Among authors: bigger bw. Mol Ther Methods Clin Dev. 2023 Oct 20;31:101127. doi: 10.1016/j.omtm.2023.101127. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 37920237 Free PMC article.

10

Mucopolysaccharide diseases: a complex interplay between neuroinflammation, microglial activation and adaptive immunity.

Archer LD, Langford-Smith KJ, Bigger BW, Fildes JE. Archer LD, et al. Among authors: bigger bw. J Inherit Metab Dis. 2014 Jan;37(1):1-12. doi: 10.1007/s10545-013-9613-3. Epub 2013 May 8. J Inherit Metab Dis. 2014. PMID: 23653226 Review.

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