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Showing results for brain konig
Search for Brian Konig instead (1 results)
The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2.
Krasemann S, Haferkamp U, Pfefferle S, Woo MS, Heinrich F, Schweizer M, Appelt-Menzel A, Cubukova A, Barenberg J, Leu J, Hartmann K, Thies E, Littau JL, Sepulveda-Falla D, Zhang L, Ton K, Liang Y, Matschke J, Ricklefs F, Sauvigny T, Sperhake J, Fitzek A, Gerhartl A, Brachner A, Geiger N, König EM, Bodem J, Franzenburg S, Franke A, Moese S, Müller FJ, Geisslinger G, Claussen C, Kannt A, Zaliani A, Gribbon P, Ondruschka B, Neuhaus W, Friese MA, Glatzel M, Pless O. Krasemann S, et al. Stem Cell Reports. 2022 Feb 8;17(2):307-320. doi: 10.1016/j.stemcr.2021.12.011. Epub 2022 Jan 20. Stem Cell Reports. 2022. PMID: 35063125 Free PMC article.
Neurological complications are common in COVID-19. Although SARS-CoV-2 has been detected in patients' brain tissues, its entry routes and resulting consequences are not well understood. ...Together, our data provide strong support for SARS-CoV-2 brain entry across t …
Neurological complications are common in COVID-19. Although SARS-CoV-2 has been detected in patients' brain tissues, its entry routes …
Multi-Strain Probiotic Mixture Affects Brain Morphology and Resting State Brain Function in Healthy Subjects: An RCT.
Rode J, Edebol Carlman HMT, König J, Hutchinson AN, Thunberg P, Persson J, Brummer RJ. Rode J, et al. Cells. 2022 Sep 19;11(18):2922. doi: 10.3390/cells11182922. Cells. 2022. PMID: 36139496 Free PMC article. Clinical Trial.
Probiotics can alter brain function via the gut-brain axis. We investigated the effect of a probiotic mixture containing Bifidobacterium longum, Lactobacillus helveticus and Lactiplantibacillus plantarum. ...The combination of those parameters may provide new insigh …
Probiotics can alter brain function via the gut-brain axis. We investigated the effect of a probiotic mixture containing Bifid …
Brain dysfunction in tubular and tubulointerstitial kidney diseases.
Viggiano D, Bruchfeld A, Carriazo S, de Donato A, Endlich N, Ferreira AC, Figurek A, Fouque D, Franssen CFM, Giannakou K, Goumenos D, Hoorn EJ, Nitsch D, Ortiz A, Pešić V, Rastenyté D, Soler MJ, Rroji M, Trepiccione F, Unwin RJ, Wagner CA, Wieçek A, Zacchia M, Zoccali C, Capasso G; CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target). Viggiano D, et al. Nephrol Dial Transplant. 2021 Dec 28;37(Suppl 2):ii46-ii55. doi: 10.1093/ndt/gfab276. Nephrol Dial Transplant. 2021. PMID: 34792176 Free PMC article. Review.
The available literature suggests that brain dysfunction in tubular and tubulointerstitial diseases is usually mild and is more often seen in disorders of water handling. Brain dysfunction may occur when severe electrolyte and water disorders in young children persi …
The available literature suggests that brain dysfunction in tubular and tubulointerstitial diseases is usually mild and is more often …
Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease: Research outline and call for collaboration.
Lathe R, Schultek NM, Balin BJ, Ehrlich GD, Auber LA, Perry G, Breitschwerdt EB, Corry DB, Doty RL, Rissman RA, Nara PL, Itzhaki R, Eimer WA, Tanzi RE; Intracell Research Group Consortium Collaborators. Lathe R, et al. Alzheimers Dement. 2023 Nov;19(11):5209-5231. doi: 10.1002/alz.13076. Epub 2023 Jun 7. Alzheimers Dement. 2023. PMID: 37283269 Free PMC article. Review.
Microbial infections of the brain can lead to dementia, and for many decades microbial infections have been implicated in Alzheimer's disease (AD) pathology. However, a causal role for infection in AD remains contentious, and the lack of standardized detection methodologie …
Microbial infections of the brain can lead to dementia, and for many decades microbial infections have been implicated in Alzheimer's …
Does thiamine protect the brain from iron overload and alcohol-related dementia?
Listabarth S, König D, Vyssoki B, Hametner S. Listabarth S, et al. Alzheimers Dement. 2020 Nov;16(11):1591-1595. doi: 10.1002/alz.12146. Epub 2020 Aug 18. Alzheimers Dement. 2020. PMID: 32808749 Free PMC article. Review.
Furthermore, we suggest thiamine, which is frequently depleted in AUD, to be a key modulator in this process: Thiamine deficiency impairs the integrity of the blood-brain barrier, thereby enabling iron to pass through and accumulate in the brain. ...To validate this …
Furthermore, we suggest thiamine, which is frequently depleted in AUD, to be a key modulator in this process: Thiamine deficiency impairs th …
Brain metastases in gastroesophageal cancers-an underestimated complication.
Brunner M, Soll D, Adler K, Sasse A, König U, Mekolli A, Lowes K, Reinecke J, Ellenrieder V, König A. Brunner M, et al. Gastric Cancer. 2022 Jan;25(1):161-169. doi: 10.1007/s10120-021-01219-z. Epub 2021 Jul 23. Gastric Cancer. 2022. PMID: 34297239 Free PMC article.
BACKGROUND: Brain metastases represent a severe complication in many gastrointestinal malignancies especially those arising from the upper gastrointestinal tract, including cancer of the esophagus, gastroesophageal junction, and stomach (GEC). However, there is little know …
BACKGROUND: Brain metastases represent a severe complication in many gastrointestinal malignancies especially those arising from the …
[Crossed Aphasia].
Schorl M, Förster B, Kropff I, Vasquez MP. Schorl M, et al. Fortschr Neurol Psychiatr. 2017 Jan;85(1):34-42. doi: 10.1055/s-0042-119028. Epub 2017 Jan 23. Fortschr Neurol Psychiatr. 2017. PMID: 28114692 Review. German.
Crossed aphasia (CA) is a rare acquired language disorder caused by a right-sided brain lesion in dextrals. Based on a case report, relevant aspects for the diagnosis of CA and differential diagnoses will be outlined. ...
Crossed aphasia (CA) is a rare acquired language disorder caused by a right-sided brain lesion in dextrals. Based on a case report, r …
Overcoming the blood-brain barrier? - prediction of blood-brain permeability of hydrophobically modified polyethylenimine polyplexes for siRNA delivery into the brain with in vitro and in vivo models.
Hartl N, Gabold B, Adams F, Uhl P, Oerter S, Gätzner S, Metzger M, König AC, Hauck SM, Appelt-Menzel A, Mier W, Fricker G, Merkel OM. Hartl N, et al. J Control Release. 2023 Aug;360:613-629. doi: 10.1016/j.jconrel.2023.07.019. Epub 2023 Jul 15. J Control Release. 2023. PMID: 37437848
The blood-brain barrier (BBB) is a highly selective biological barrier that represents a major bottleneck in the treatment of all types of central nervous system (CNS) disorders. Small interfering RNA (siRNA) offers in principle a promising therapeutic approach, e.g., for …
The blood-brain barrier (BBB) is a highly selective biological barrier that represents a major bottleneck in the treatment of all typ …
The SARS-CoV-2 main protease M(pro) causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.
Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner JUG, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho CFF, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen HC, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M. Wenzel J, et al. Nat Neurosci. 2021 Nov;24(11):1522-1533. doi: 10.1038/s41593-021-00926-1. Epub 2021 Oct 21. Nat Neurosci. 2021. PMID: 34675436 Free PMC article.
We obtained evidence that brain endothelial cells are infected and that the main protease of SARS-CoV-2 (M(pro)) cleaves NEMO, the essential modulator of nuclear factor-kappaB. By ablating NEMO, M(pro) induces the death of human brain endothelial cells and the occur …
We obtained evidence that brain endothelial cells are infected and that the main protease of SARS-CoV-2 (M(pro)) cleaves NEMO, the es …
Brain perfusion CT in acute stroke: current status.
König M. König M. Eur J Radiol. 2003 Mar;45 Suppl 1:S11-22. doi: 10.1016/s0720-048x(02)00359-5. Eur J Radiol. 2003. PMID: 12598022 Review.
Two theoretical concepts have been described for the calculation of tissue perfusion from contrast bolus studies, both of which can be equally employed for brain perfusion imaging. For each perfusion model there are some profound limitations regarding the validity of perfu …
Two theoretical concepts have been described for the calculation of tissue perfusion from contrast bolus studies, both of which can be equal …
918 results